Dr. SASWAT KUMAR MOHANTY

About

Dedicated to unravelling aging's intricacies, I am a seasoned aging biochemist specializing in healthy aging, organ vitality, and novel strategies for age-related disease prevention and therapies. My primary focus revolves around the transformative potential of the anti-aging protein, Klotho, with the aim of revolutionizing therapeutic paradigms for aging-related conditions. With a wealth of experience and an unwavering commitment to pushing scientific boundaries, I aspire to contribute impactful solutions that empower individuals to age with resilience and vitality.

Employment

• Brown University PostDoc
  2024 - Present
• Pondicherry University JUNIOR RESEARCH FELLOW
  2017 - 2018

Education

• Pondicherry University PhD
  2018 - 2023
• Pondicherry University M.Sc
  2014 - 2016
• Orissa University of Agriculture and Technology BACHELOR IN SCIENCE (HONOURS)
  2011 - 2014
• Brown University

Projects & Funding

Projects & funding information is unavailable.

Publications (10)

• Exploration of mechanism of anticancer potential of fisetin nanoformulations: nanotized fisetin/fisetin loaded polymannose nanoparticles in the treatment of triple negative breast carcinoma
  3 Biotech 2025 DOI: 10.1007/s13205-025-04427-x
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• Bidirectional upregulation of Klotho by triiodothyronine and baicalein: mitigating chronic kidney disease and associated complications in aged BALB/c mice
  Biogerontology 2025 DOI: 10.1007/s10522-025-10257-4
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• Age-related disease: Kidneys
  Aging 2024 DOI: 10.1016/B978-0-443-15500-0.00003-7
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• Triiodothyronine enhances various forms of kidney-specific Klotho protein and suppresses the Wnt/β-catenin pathway: Insights from in-vitro, in-vivo and in-silico investigations
  Cellular Signalling 2024 DOI: 10.1016/J.CELLSIG.2024.111214
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• Baicalein mitigates oxidative stress and enhances lifespan through modulation of Wnt ligands and GATA factor: ELT-3 in Caenorhabditis elegans
  Life Sciences 2023 DOI: 10.1016/j.lfs.2023.121946
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• Triiodothyronine (T3) enhances lifespan and protects against oxidative stress via activation of Klotho in Caenorhabditis elegans
  Biogerontology 2021 DOI: 10.1007/s10522-021-09923-0
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• Anti-quorum sensing and anti-biofilm activity of 5-hydroxymethylfurfural against Pseudomonas aeruginosa PAO1: Insights from in vitro, in vivo and in silico studies
  2019 DOI: 10.1016/j.micres.2019.05.001
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• Mosloflavone attenuates the quorum sensing controlled virulence phenotypes and biofilm formation in Pseudomonas aeruginosa PAO1: In vitro, in vivo and in silico approach
  Microbial Pathogenesis 2019 DOI: 10.1016/j.micpath.2019.04.005
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• Attenuation of quorum sensing controlled virulence factors and biofilm formation in Pseudomonas aeruginosa by pentacyclic triterpenes, betulin and betulinic acid
  Microbial Pathogenesis 2018 DOI: 10.1016/j.micpath.2018.03.012
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• Cinnamic acid attenuates quorum sensing associated virulence factors and biofilm formation in Pseudomonas aeruginosa PAO1
  Biotechnology Letters 2018 DOI: https://doi.org/10.1007/s10529-018-2557-9
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