AH

Alastair Hotblack

University College London

ORCID iD 0000-0002-6214-2296

Employment

  • University College London Senior Research Fellow

Education

Education history is unavailable.

Projects & Funding

Projects & funding information is unavailable.

Publications (14)

  • Designer small-molecule control system based on minocycline-induced disruption of protein--protein interaction
    ACS Chemical Biology 2024
    +Save
  • AKT inhibition generates potent polyfunctional clinical grade AUTO1 CAR T-cells, enhancing function and survival
    Journal for ImmunoTherapy of Cancer 2023
    +Save
  • Fine-tuning CARs for best performance
    Cancer Cell 2022
    +Save
  • IMMU-16. Next-generation CAR T-cells targeting IL13RA2 and secreting IL-15 achieve durable tumour clearance in pre-clinical model of diffuse midline glioma
    Neuro-Oncology 2022
    +Save
  • P1460: SAFETY AND EFFICACY FINDINGS OF AUTO1, A FAST-OFF RATE CD19 CAR, IN RELAPSED/REFRACTORY PRIMARY CNS LYMPHOMA
    HemaSphere 2022
    +Save
  • Intratumoral IL-12 delivery empowers CAR-T cell immunotherapy in a pre-clinical model of glioblastoma
    Nature Communications 2021 DOI: 10.1038/s41467-020-20599-x
    +Save
  • Tunable control of CAR T cell activity through tetracycline mediated disruption of protein--protein interaction
    Scientific Reports 2021
    +Save
  • Regulatory T cells restrain interleukin-2-and Blimp-1-dependent acquisition of cytotoxic function by CD4+ T cells
    Immunity 2020
    +Save
  • Near-infrared dual bioluminescence imaging in mouse models of cancer using infraluciferin
    Elife 2019
    +Save
  • Tumor-resident dendritic cells and macrophages modulate the accumulation of TCR-engineered T cells in melanoma
    Molecular Therapy 2018
    +Save