Denes Hnisz

Employment

• Max Planck Institute for Molecular Genetics Group Leader
  2018 - Present

Education

Education history is unavailable.

Projects & Funding

Projects & funding information is unavailable.

Publications (43)

• Oligomerization enables the selective targeting of an intrinsically disordered region by a small molecule
  Science Advances 2026 DOI: 10.1126/sciadv.adz7400
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• Probing condensate microenvironments with a micropeptide killswitch
  Nature 2025 DOI: 10.1038/s41586-025-09141-5
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• Differential oligomerization regulates PHF13 chromatin affinity and function
  Nucleic Acids Research 2025 DOI: 10.1093/nar/gkaf572
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• Transcription factor condensates: Preventing aggregation by DNA binding
  Cell 2025 DOI: 10.1016/j.cell.2025.04.034
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• Functional specificity in biomolecular condensates revealed by genetic complementation
  Nature Reviews Genetics 2025 DOI: 10.1038/s41576-024-00780-4
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• An activity-specificity trade-off encoded in human transcription factors
  Nature Cell Biology 2024 DOI: 10.1038/s41556-024-01411-0
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• Rational optimization of a transcription factor activation domain inhibitor
  Shaon Basu, Paula Martínez-Cristóbal, Marta Frigolé‐Vivas +34 more
  Nature Structural & Molecular Biology 2023 DOI: 10.1038/s41594-023-01159-5
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• High-sensitive nascent transcript sequencing reveals BRD4-specific control of widespread enhancer and target gene transcription
  Nature Communications 2023 DOI: 10.1038/s41467-023-40633-y
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• CEBPA phase separation links transcriptional activity and 3D chromatin hubs
  Cell Reports 2023 DOI: 10.1016/j.celrep.2023.112897
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• Regulatory architecture of housekeeping genes is driven by promoter assemblies
  Cell Reports 2023 DOI: 10.1016/j.celrep.2023.112505
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• Aberrant phase separation and nucleolar dysfunction in rare genetic diseases
  Nature 2023 DOI: 10.1038/s41586-022-05682-1
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• T-REX17 is a transiently expressed non-coding RNA essential for human endoderm formation
  eLife 2023 DOI: 10.7554/elife.83077
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• Hijacking of transcriptional condensates by endogenous retroviruses
  Nature Genetics 2022 DOI: 10.1038/s41588-022-01132-w
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• STAG2 loss rewires oncogenic and developmental programs to promote metastasis in Ewing sarcoma
  Cancer Cell 2021 DOI: 10.1016/j.ccell.2021.05.007
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• Integration of multiomics data with graph convolutional networks to identify new cancer genes and their associated molecular mechanisms
  Nature Machine Intelligence 2021 DOI: 10.1038/s42256-021-00325-y
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• Selective Mediator dependence of cell-type-specifying transcription
  Nature Genetics 2020 DOI: 10.1038/s41588-020-0635-0
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• Unblending of Transcriptional Condensates in Human Repeat Expansion Disease
  Cell 2020 DOI: 10.1016/j.cell.2020.04.018
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• Graph Convolutional Networks Improve the Prediction of Cancer Driver Genes
  2019 DOI: 10.1007/978-3-030-30493-5_60
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• Coactivator condensation at super-enhancers links phase separation and gene control.
  Science (New York, N.Y.) 2018 DOI: 10.1126/science.aar3958
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• Transcriptional Dysregulation of MYC Reveals Common Enhancer-Docking Mechanism.
  Cell reports 2018 DOI: 10.1016/j.celrep.2018.03.056
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