Khemraj Bairwa

About

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Professional Synopsis:
Dr. Khemraj Bairwa is an experienced researcher, educator, and expert in natural products, particularly focused on the discovery of bioactive constituents from terrestrial, microbial, and marine sources. He has a strong background in analytical and spectroscopic techniques, including HPLC, UPLC, LC-MS, GC-MS, and NMR. Dr. Bairwa has been awarded the PharmInnova Best Ph.D. Thesis Award 2016, organized by the Rajnibhai V. Patel Trust, under the patronage of the Department of Science and Technology, Govt. of India.
He currently serves as a Senior Research Investigator at Biocon-BMS R&D Center (BBRC), Bengaluru, India, and has significant teaching experience as a faculty member at the National Institute of Pharmaceutical Education and Research (NIPER), Ahmedabad, where he mentors master’s and Ph.D. students.
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Dr. Bairwa has worked extensively with HPLC method development, LC-MS/MS analysis, and preparative purification of bioactive compounds.
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Core Competencies:
• Chiral and achiral purification of small molecules
• HPLC/UPLC, LC-MS, GC-MS, Prep-HPLC
• Structure elucidation using 1D and 2D NMR
• Bioactive compound isolation from natural sources
• Development of nanoformulations for phytoconstituents
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Research Interests:
• Development of innovative purification methods utilizing green, sustainable solvents and advanced stationary phases
• Discovery of new chemical entities from natural products
• Q-marker based standardization of herbal extracts
• Cancer and diabetes therapeutic research using bioactive natural products
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Honors and Awards:
• 2016: PharmInnova Best Ph.D. Thesis Award (INR 75,000 Cash Prize)
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Publications:
Dr. Bairwa has published multiple high-impact research articles on natural products, analytical techniques, and bioactive compound development. Some of his notable publications include works in Journal of Natural Products, Phytochemical Analysis, Pharmaceutical Biology, RSC Advances, Chromatographia, Green Analytical Chemistry, Phytomedicine, Phytochemistry Review, etc.
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Conferences and Workshops:
Dr. Bairwa has participated in numerous international conferences, workshops, and symposia, presenting his research on phytochemical investigations, biological evaluation, and pharmacological studies. He has also organized workshops, including one on LC-MS/MS applications in natural product research at NIPER-Ahmedabad.
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Dr. Khemraj Bairwa's expertise in natural product research, analytical techniques, and his dedication to mentoring students has made significant contributions to the field of pharmaceutical sciences and bioactive compound discovery.

Employment

• Biocon-Bristol Myers Squibb Research & Development Center (BBRC) Senior Research Investigator
  2020 - Present
• National Institute of Pharmaceutical Education and Research Ahmedabad Post Doc Fellow
  2018 - 2020
• Dr. KN Modi University Assistant Professor and Head
  2016 - 2018
• Trivedi Science Laboratory Nutraceutical Scientist
  2015 - 2015
• Dr KN Modi Institute of Pharmaceutical Sciences and Research Lectrurer
  2010 - 2010

Education

• NIPER SAS Nagar Ph D
  2010 - 2015
• NIPER SAS Nagar M. S. Pharm
  2007 - 2009

Projects & Funding

Projects & funding information is unavailable.

Publications (21)

• Identification and characterization of a novel ergothioneine conjugate of raloxifene
  Drug Metabolism and Disposition 2025 DOI: 10.1016/j.dmd.2024.100034
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• High throughput and cost-effective purification of small molecules using superficially porous stationary phase columns: An environment friendly approach
  Green Analytical Chemistry 2024 DOI: 10.1016/j.greeac.2024.100163
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• Leveraging Superficially Porous Particle Technology to Develop High-Throughput HPLC Methods for Small-Molecule Drug Discovery
  Chromatographia 2023 DOI: 10.1007/s10337-023-04259-y
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• Herbal nanomedicines: Recent advancements, challenges, opportunities and regulatory overview
  Phytomedicine 2022 DOI: 10.1016/j.phymed.2021.153890
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• Isolation and Identification of Pinocembrin-7-O-[4”, 6"-(S)-Hexahydroxy Diphenoyl]-β-D-Glucose from Macrosolen capitellatus: In vitro and In silico Studies to Explore its Anticancer Potential
  Journal of Biologically Active Products from Nature 2020 DOI: 10.1080/22311866.2020.1791732
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• Pharmaceutical perspective on bioactives from Alstonia scholaris: ethnomedicinal knowledge, phytochemistry, clinical status, patent space, and future directions
  Phytochemistry Reviews 2020 DOI: 10.1007/s11101-020-09662-z
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• Nanoparticle formulation of 11-keto-β-boswellic acid (KBA): anti-inflammatory activity and in vivo pharmacokinetics
  Pharmaceutical Biology 2016 DOI: 10.1080/13880209.2016.1194437
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• Determination of negundoside and agnuside in Vitex negundo by qNMR and method validation.
  Journal of Analytical Chemistry 2015
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• 2′-Hydroxy flavanone derivatives as an inhibitors of pro-inflammatory mediators: Experimental and molecular docking studies
  Bioorganic & Medicinal Chemistry Letters 2015 DOI: 10.1016/j.bmcl.2015.03.025
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• Anti-inflammatory potential of a lipid-based formulation of a rotenoid-rich fraction prepared fromBoerhavia diffusa
  Pharmaceutical Biology 2015 DOI: 10.3109/13880209.2014.971382
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