GT
Gatha Thacker
Central University of Rajasthan, The Wistar Institute, Central Drug Research Institute, Annamalai University, University of Miami Health System, Dr. Hari Singh Gour University
Research areas: Medicine · Oncology · Ubiquitin and proteasome pathways · Cancer Immunotherapy and Biomarkers · Cancer Cells and Metastasis
0000-0002-6378-4442
Employment
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Central University of Rajasthan Assistant Profesor2026 - Present
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The Wistar Institute Staff Scientist2023 - 2026
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University of Miami Health System Postdoctoral Research Associate2022 - 2023
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University of Pennsylvania Postdoctoral fellow2019 - 2022
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Guru Ghasidas Central University Assistant professor Ad-hoc2012 - 2012
Education
- 2014 - 2019
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Annamalai University M.Sc.2009 - 2011
- 2006 - 2009
Projects & Funding
Projects & funding information is unavailable.
Publications (27)
- Melanoma-patient-derived xenograft multi-omics resource melPDomiX maps gain- and loss-of-function alterations. Save
- KRT17 promotes triple negative breast cancer through activation of Wnt signaling and γδ T-cells recruitment Save
- Clonal dynamics shaped by diverse drug-tolerant persister states in melanoma resistance. Save
- The landscape of gain and loss of function mutations in melanoma Save
- Nemo-like kinase blocks myeloid differentiation by targeting tumor suppressor C/EBPα in AML. Save
- Immature natural killer cells promote progression of triple-negative breast cancer Save
- Ormeloxifene, a nonsteroidal antifertility drug promotes megakaryocyte differentiation in leukemia cell line K562 Save
- Dll1-Mediated Notch Signaling Drives Tumor Cell Cross-talk with Cancer-Associated Fibroblasts to Promote Radioresistance in Breast Cancer. Save
- SOX4-mediated FBW7 transcriptional upregulation confers Tamoxifen resistance in ER+ breast cancers via GATA3 downregulation. Save
- CDK2-instigates C/EBPα degradation through SKP2 in Acute myeloid leukemia. Save
- Proteomic analysis of TGFβ-induced A549 secretome identifies putative regulators of epithelial-mesenchymal transition. Save
- Author Correction: Loss of ELF5–FBXW7 stabilizes IFNGR1 to promote the growth and metastasis of triple-negative breast cancer through interferon-γ signalling (Nature Cell Biology, (2020), 22, 5, (591-602), 10.1038/s41556-020-0495-y) Save
- FBW7 Inhibits Myeloid Differentiation in Acute Myeloid Leukemia via GSK3-Dependent Ubiquitination of PU.1. Save
- Chebulinic acid inhibits MDA-MB-231 breast cancer metastasis and promotes cell death through down regulation of SOD1 and induction of autophagy. Save
- E3 ligase SCFSKP2 ubiquitinates and degrades tumor suppressor C/EBPα in acute myeloid leukemia. Save
- CDK2 destabilizes tumor suppressor C/EBPα expression through ubiquitin-mediated proteasome degradation in acute myeloid leukemia Save
- Loss of ELF5–FBXW7 stabilizes IFNGR1 to promote the growth and metastasis of triple-negative breast cancer through interferon-γ signalling Save
- CDK2 destabilizes tumor suppressor C/EBPα expression through ubiquitin-mediated proteasome degradation in acute myeloid leukemia. Save
- Nano-LC based proteomic approach identifies that E6AP interacts with ENO1 and targets it for degradation in breast cancer cells. Save
- Nano-LC based proteomic approach identifies that E6AP interacts with ENO1 and targets it for degradation in breast cancer cells Save