Simran Arora
Baba Farid University of Health Sciences, Tata Institute of Fundamental Research, Guru Nanak Dev University
0000-0002-6423-4442
About
I am a Postdoctoral Associate in the Department of Chemistry at Rice University, where I study the molecular mechanisms underlying protein aggregation in neurodegenerative diseases. I got my Ph.D. from Protein Biophysics lab from the Tata Institute of Fundamental Research, Mumbai, where I investigated how post-translational modifications such as ubiquitination and SUMOylation regulate protein structure, stability, and phase separation. My current work focuses on α-synuclein, exploring how liquid–liquid phase separation (LLPS) acts as an intermediate in its aggregation pathway. By combining biophysical, biochemical, and imaging tools, I aim to understand how these molecular processes contribute to disease and to guide the design of novel therapeutic strategies.
Employment
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Baba Farid University of Health Sciences College Lecturer2018 - 2019
Education
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Tata Institute of Fundamental Research Ph.D. Research Scholar2019 - 2024
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Guru Nanak Dev University Bachelor's in Chemistry2013 - 2016
Projects & Funding
Projects & funding information is unavailable.
Publications (6)
- Phase Separation of Parkinson's Disease Protein α‐Synuclein: Mechanistic Insights but Biological Uncertainties Save
- Protein Stability Regulated by Tag- and Site-Specific Ubiquitination and SUMOylation Save
- Electrostatics Govern Protein Orientation on Citrate-Capped Gold Nanoparticles Save
- Probing Aromatic Side Chains Reveals the Site-Specific Melting in the SUMO1 Molten Globule Save
- Phase Separation and Aggregation of a Globular Folded Protein Small Ubiquitin-like Modifier 1 (SUMO1) Save
- Liquid-liquid phase separation and aggregation of a globular folded protein SUMO1 Save