WY
Wen-Bin Yang
Taipei Medical University, National Chiao Tung University College of Biological Science and Technology, National Cheng Kung University, National Chiayi University, National Health Research Institutes
Research areas: Chemistry · Organic Chemistry · Glioma Diagnosis and Treatment · Carbohydrate Chemistry and Synthesis · Glycosylation and Glycoproteins Research
Employment
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Taipei Medical University Assistant Professor2024 - Present
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Taipei Medical University Assistant Research Fellow2021 - 2024
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Taipei Medical University Postdoctoral Fellow2017 - 2021
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National Chiao Tung University College of Biological Science and Technology Postdoctoral Fellow2016 - 2017
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National Health Research Institutes Postdoctoral Fellow2015 - 2016
Education
- 2009 - 2014
- 2007 - 2009
- 2003 - 2007
Projects & Funding
Projects & funding information is unavailable.
Publications (31)
- Dual SYK-HDAC Inhibitor Elicits Striking Efficacy against Acute Myeloid Leukemia: Rational Design, Synthesis, and Biological Evaluation Save
- A novel dual CDC25-HDAC inhibitor suppresses glioblastoma progression via chromosomal passenger complex disruption. Save
- Chitinase-3-like-1: a multifaceted player in neuroinflammation and degenerative pathologies with therapeutic implications Save
- Progesterone boosts abiraterone-driven target and NK cell therapies against glioblastoma Save
- CXCR7 activation evokes the anti-PD-L1 antibody against glioblastoma by remodeling CXCL12-mediated immunity Save
- Dual inhibition of CYP17A1 and HDAC6 by abiraterone-installed hydroxamic acid overcomes temozolomide resistance in glioblastoma through inducing DNA damage and oxidative stress Save
- First-in-Class Dual EZH2-HSP90 Inhibitor Eliciting Striking Antiglioblastoma Activity In Vitro and In Vivo Save
- Dysregulated lipid metabolism in TMZ-resistant glioblastoma: pathways, proteins, metabolites and therapeutic opportunities Save
- SH3GLB1-related autophagy mediates mitochondrial metabolism to acquire resistance against temozolomide in glioblastoma. Save
- Reprogramming of arachidonate metabolism confers temozolomide resistance to glioblastoma through enhancing mitochondrial activity in fatty acid oxidation. Save
- HDAC6 involves in regulating the lncRNA-microRNA-mRNA network to promote the proliferation of glioblastoma cells. Save
- CCAAT/Enhancer‐Binding Protein Delta Regulates Glioblastoma Survival through Catalase‐Mediated Hydrogen Peroxide Clearance Save
- Estradiol-mediated inhibition of Sp1 decreases miR-3194-5p expression to enhance CD44 expression during lung cancer progression Save
- Histone deacetylase 6 acts upstream of DNA damage response activation to support the survival of glioblastoma cells Save
- Reprogramming of arachidonate metabolism confers drug resistance to glioblastoma through Enhancing Mitochondrial Activity in Fatty Acid Oxidation Save
- Red LED light treatment promotes cognitive learning through up-regulation of trpm4 in zebrafish. Save
- Betulinic Acid-Mediated Tuning of PERK/CHOP Signaling by Sp1 Inhibition as a Novel Therapeutic Strategy for Glioblastoma Save
- Increased activation of HDAC1/2/6 and Sp1 underlies therapeutic resistance and tumor growth in glioblastoma. Save
- ANGPTL4 Induces TMZ Resistance of Glioblastoma by Promoting Cancer Stemness Enrichment via the EGFR/AKT/4E-BP1 Cascade Save
- CYP17A1 Maintains the Survival of Glioblastomas by Regulating SAR1-Mediated Endoplasmic Reticulum Health and Redox Homeostasis Save