Dr. Narsinh Dodia

About

I am Dr. Narsinh Dodia, Doctorate in Medicinal chemistry from Saurashtra University, Rajkot, India. I have vast experience in Organic chemistry, Medicinal chemistry, Active Pharmaceutical Ingredient (API) . Completed my postdocorate from Institute of Biomedical Sciences (IBMS), Academia Sinica, Taipei, Taiwan. My post doctorate was specific to N-mustard (DNA-Alkylating Agent) and biological evaluation for Anticancer activity. I have profession experience in Medicinal chemistry, Drug Development, New chemical Entities (NCE), Process Research, Technology transfer, Scale up study, Process Robustness study. I have worked with Custom Research Organization (CROs) , API manufacturing organization . I have started my career with CRO and move to process research organization where the route scouting, Proof of concept and costing calculation activity were performed. The approved project to be executed in laboratory followed by communication and interaction with customer. The current work portfolio is to manage group of team and execution of bench work. Currently I am working with the Zentiva Pvt. Ltd as Manager-Process Research and Development.
I have additional responsibility to manage LEAN tool for the Pharmaceutical Development

Employment

• Zentiva Manager- Process Research and Development
  2020 - Present
• Sanofi India Ltd Manager-Process Research and Development
  2012 - 2020
• Gujarat Fluoro Chemicals Ltd Manager-R & D
  2012 - 2012
• Surya Pharmaceutical Ltd Group Leader- R & D
  2009 - 2012
• Academia Sinica Post Doctorate Fellow
  2007 - 2008
• Jubilant Organosys Ltd Research Scientist
  2004 - 2006
• Enzal Chemicals India Ltd R & D-Officer
  2003 - 2004
• Uma Laboratories Pvt Ltd Research Officer
  2001 - 2003
• Hoechst Marion Roussel Trainee-Chemist
  2000 - 2001

Education

• Saurashtra University Master of Science-Analytical Chemistry
  1995 - 1996
• Saurashtra University Bachelor of Science-Chemistry
  1991 - 1994

Projects & Funding

Projects & funding information is unavailable.

Publications (21)

• Synthesis and antimicrobial activity of {2-amino/2-methoxy}-4-(2’-n-butyl-4’-chloro-1’-H-imidazol-5’-yl)-6-aryl nicotinonitriles
  World News of Natural Sciences 2022
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• Synthesis, spectral studies and antimicrobial activity of 2-amino-4-(2’-n-butyl-4’-chloro-1’-h-imidazol-5’-yl)-6-aryl-4-h-pyran-3-carbonitriles
  International Journal of Chemical Science 2022
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• Evaluation and in vivo efficacy study of pyrano[3,2-c]quinoline analogues as TNF-α inhibitors.
  Chemical biology & drug design 2019
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• Evaluation and in vivo efficacy study of pyrano[3,2-c]quinoline analogues as TNF-α inhibitors
  Chemical Biology and Drug Design 2019 DOI: 10.1111/cbdd.13566
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• Synthesis and Biological Screening of Pyrano[3,2-c]quinoline Analogues as Anti-inflammatory and Anticancer Agents
  ACS Medicinal Chemistry Letters 2018 DOI: 10.1021/acsmedchemlett.7b00545
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• Synthesis and binary QSAR study of antitubercular quinolylhydrazides
  Bioorganic Medicinal Chemistry Letters 2013 DOI: 10.1016/j.bmcl.2013.06.076
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• Diversity oriented design of various hydrazides and their in vitro evaluation against Mycobacterium tuberculosis H37Rv strains
  Bioorganic & Medicinal Chemistry Letters 2011 DOI: 10.1016/j.bmcl.2011.06.074
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• Potent DNA-directed alkylating agents: Synthesis and biological activity of phenyl N-mustard-quinoline conjugates having a urea or hydrazinecarboxamide linker.
  Bioorganic & medicinal chemistry 2010 DOI: 10.1016/j.bmc.2010.01.061
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• Novel oxidative nitrogen to carbon rearrangement found in the conversion of anilines to benzaldoximes by treating with HCHO/H2O2
  Tetrahedron Letter 2008
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• Novel oxidative nitrogen to carbon rearrangement found in the conversion of anilines to benzaldoximes by treating with HCHO/H2O2
  Tetrahedron Letters 2008 DOI: 10.1016/j.tetlet.2008.03.033
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