Pundi Rangarajan

About

Yeast strains expressing Hepatitis B surface antigen developed in our laboratory are being used for commercial production of Recombinant Hepatitis B vaccines which are currently being marketed as BEVAC (monovalent), ELOVAC-B (monovalent) and ComBE FIVE and VAXTAR-5 (pentavalent).

Current research is focussed on the study of metabolism, gene regulation and signalling pathways of the methylotrophic yeast, Pichia pastoris.

Employment

• Indian Institute of Science Professor
  1994 - Present

Education

• Indian Institute of Science PhD
  1984 - 1989

Projects & Funding

Projects & funding information is unavailable.

Publications (80)

• Dual transcriptional and post-transcriptional regulation by the bHLH proteins Rtg1 and RtgX in Komagataella phaffii
  Nucleic Acids Research 2026 DOI: 10.1093/nar/gkaf1475
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• Histidine is essential for growth of Komagataella phaffii cultured in YPA medium
  FEBS Open Bio 2022 DOI: 10.1002/2211-5463.13408
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• Minus one frameshifted puromycin N-acetyltransferase is targeted to the nucleolus: sporadic but reproducible chimera formation by a transfected Lc3b construct
  2022 DOI: 10.1101/2022.02.17.480764
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• Characterization of the transactivation and nuclear localization functions of Pichia pastoris zinc finger transcription factor Mxr1p
  Journal of Biological Chemistry 2021 DOI: 10.1016/j.jbc.2021.101247
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• Post-transcriptional regulation of glutamate metabolism ofPichia pastorisand development of a glutamate-inducible yeast expression system
  2021 DOI: 10.1101/2021.03.10.434748
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• Function and regulation of an aldehyde dehydrogenase essential for ethanol and methanol metabolism of the yeast, Komagataella phaffii
  2020 DOI: 10.1101/2020.06.14.151365
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• Apolipoprotein L9 interacts with LC3/GABARAP and is a microtubule-associated protein with a widespread subcellular distribution
  2019 DOI: 10.1101/671065
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• Apolipoprotein L9 interacts with LC3/GABARAP and is a microtubule-associated protein with a widespread subcellular distribution
  Biology Open 2019 DOI: 10.1242/bio.045930
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• The nuclear transcription factor Rtg1p functions as a cytosolic, post-transcriptional regulator in the methylotrophic yeast Pichia pastoris
  Journal of Biological Chemistry 2018 DOI: 10.1074/jbc.RA118.004486
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• Methionine synthase is localized to the nucleus in Pichia pastoris and Candida albicans and to the cytoplasm in Saccharomyces cerevisiae.
  2017
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