KA
Employment
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University of California San Diego Postdoctoral assistant2016 - 2019
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University of Waterloo
Education
Education history is unavailable.
Projects & Funding
Projects & funding information is unavailable.
Publications (11)
- Advancing Structural Biology and Protein-Ligand Interactions through Hydrogen/Deuterium Exchange Mass Spectrometry (HDX-MS) Save
- Avoidance of the use of tryptophan in buried chromosomal proteins as a mechanism for reducing photo/oxidative damage to genomes Save
- The bacterial nucleoid-associated proteins, HU and Dps, condense DNA into context-dependent biphasic or multiphasic complex coacervates Save
- HU-AB simulacrum: Fusion of HU-B and HU-A into HU-B-A, a functional analog of the Escherichia coli HU-AB heterodimer Save
- N-Terminal Extensions Appear to Frustrate HU Heterodimer Formation by Strengthening Intersubunit Contacts and Blocking the Formation of a Heterotetrameric Intermediate Save
- The DNA-binding protein HU is a molecular glue that attaches bacteria to extracellular DNA in biofilms Save
- The conserved XPF:ERCC1-like Zip2:Spo16 complex controls meiotic crossover formation through structure-specific DNA binding Save
- The achilles' heel of "ultrastable" hyperthermophile proteins: Submillimolar concentrations of SDS stimulate rapid conformational change, aggregation, and amyloid formation in proteins carrying overall positive charge Save
- Single cell-level detection and quantitation of leaky protein expression from any strongly regulated bacterial system Save
- Calcium binding to beta-2-microglobulin at physiological Ph drives the occurrence of conformational changes which cause the protein to precipitate into amorphous forms that subsequently transform into amyloid aggregates Save