Ajay Kumar

About

Dr. Ajay Kumar completed his M.Sc. in Life Sciences from Jawaharlal Nehru University, New Delhi, India. He completed his Ph.D. degree on the title “An investigation on the development of novel antitumor and chemosensitizing therapeutic strategies based on targeting crucial aspects of tumor metabolism by α-cyano-4-hydroxycinnamate and dichloroacetate” under the supervision of Prof Sukh Mahendra Singh from Banaras Hindu University, Varanasi, India. After obtaining his Ph.D. in 2013, he moved to the United States and did one year of postdoctoral training on the “role of lysophosphatidic acid on the progression of colon cancer” at School of Medicine, Emory University, Atlanta. After completing his postdoctoral training, he returned back to India in 2015 and continued his research in the field of tumor metabolism as a Dr. D.S. Kothari postdoctoral fellow in the laboratory of Prof. Rana Pratap Singh at School of Life Sciences, Jawaharlal Nehru University, New Delhi, for four months. In the same year, he got an Assistant Professor position at Centre for Animal Sciences, Central University of Punjab, Bathinda and he was there for two and a half months. At the end of 2015, he joined as an Assistant Professor at Department of Zoology, Banaras Hindu University. Dr. Ajay Kumar published 15 research articles, 3 review article, and 9 book chapters in internationally recognized journals and publishers. He received DST early career award from Department of Science & Technology, New Delhi and Start-up Grant from University Grants Commission, New Delhi.

Employment

• Banaras Hindu University Associate Professor
  2024 - Present

Education

• Banaras Hindu University Ph.D.
  2010 - 2013

Projects & Funding

Projects & funding information is unavailable.

Publications (16)

• Lysophosphatidic acid promotes survival of T lymphoma cells by altering apoptosis and glucose metabolism
  Apoptosis 2020 24 citations DOI: 10.1007/s10495-019-01585-1
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• Protective and recuperative effects of 3-bromopyruvate on immunological, hepatic and renal homeostasis in a murine host bearing ascitic lymphoma: Implication of niche dependent differential roles of macrophages
  Biomedicine & Pharmacotherapy 2018 16 citations DOI: 10.1016/j.biopha.2018.01.149
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• Antitumor action of 3-bromopyruvate implicates reorganized tumor growth regulatory components of tumor milieu, cell cycle arrest and induction of mitochondria-dependent tumor cell death
  Toxicology and Applied Pharmacology 2018 15 citations DOI: 10.1016/j.taap.2017.12.004
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• Molecular docking studies of 3-bromopyruvate and its derivatives to metabolic regulatory enzymes: Implication in designing of novel anticancer therapeutic strategies
  PLOS ONE 2017 96 citations DOI: 10.1371/journal.pone.0176403
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• Antitumor and chemosensitizing action of 3-bromopyruvate: Implication of deregulated metabolism
  Chemico-Biological Interactions 2017 37 citations DOI: 10.1016/j.cbi.2017.04.015
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• HIF1α-Induced by Lysophosphatidic Acid Is Stabilized via Interaction with MIF and CSN5
  PLOS ONE 2015 20 citations DOI: 10.1371/journal.pone.0137513
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• Diverse roles of LPA signaling in the intestinal epithelium
  Experimental Cell Research 2015 24 citations DOI: 10.1016/j.yexcr.2014.11.013
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• Bicarbonate transport inhibitor SITS modulates pH homeostasis triggering apoptosis of Dalton’s lymphoma: implication of novel molecular mechanisms
  Molecular and Cellular Biochemistry 2014 8 citations DOI: 10.1007/s11010-014-2184-2
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• Tumor growth retardation and chemosensitizing action of fatty acid synthase inhibitor orlistat on T cell lymphoma: Implication of reconstituted tumor microenvironment and multidrug resistance phenotype
  Biochimica et Biophysica Acta (BBA) - General Subjects 2014 50 citations DOI: 10.1016/j.bbagen.2013.09.020
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• Myelopoietic Efficacy of Orlistat in Murine Hosts Bearing T Cell Lymphoma: Implication in Macrophage Differentiation and Activation
  PLoS ONE 2013 11 citations DOI: 10.1371/journal.pone.0082396
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