Xin Lou

Employment

• Zhejiang Lab Assistant Professor
  2022 - Present
• Nanjing University Assistant Professor
  2013 - 2022
• Hospital for Sick Children Research Fellow
  2008 - 2012

Education

• Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences Ph.D
  2002 - 2008

Projects & Funding

Projects & funding information is unavailable.

Publications (18)

• An upgraded nuclease prime editor platform enables high-efficiency singled or multiplexed knock-in/knockout of genes in mouse and sheep zygotes
  Protein & Cell 2025 DOI: 10.1093/procel/pwaf006
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• Compromised COPII vesicle trafficking leads to glycogenic hepatopathy
  Disease Models & Mechanisms 2024 DOI: 10.1242/dmm.050748
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• Developing mitochondrial base editors with diverse context compatibility and high fidelity via saturated spacer library
  Nature Communications 2023 DOI: 10.1038/s41467-023-42359-3
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• Ablating all mitochondrial protein-coding genes
  Nature Biomedical Engineering 2022 DOI: 10.1038/s41551-022-00993-0
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• blf and the drl cluster synergistically regulate cell fate commitment during zebrafish primitive hematopoiesis
  Development 2022 DOI: 10.1242/dev.200919
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• Precision modeling of mitochondrial diseases in zebrafish via DdCBE-mediated mtDNA base editing
  Cell Discovery 2021 DOI: 10.1038/s41421-021-00307-9
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• The major vault protein is dispensable for zebrafish organ regeneration
  Heliyon 2020 DOI: 10.1016/j.heliyon.2020.e05422
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• 3-Difluoroalkyl Quaternary Oxindoles Inhibit Macrophage Pyroptosis by Blocking Inflammasome Recruitment of Caspase-1
  ACS Medicinal Chemistry Letters 2020 DOI: 10.1021/acsmedchemlett.0c00070
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• The DEAD-box RNA helicase Ddx39ab is essential for myocyte and lens development in zebrafish
  Development 2018 DOI: 10.1242/dev.161018
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• The DEAD box RNA helicase Ddx39a is essential for myocyte and lens development in zebrafish
  2017 DOI: 10.1101/209650
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