AA
Ali Amini
University of Oxford, London School of Hygiene & Tropical Medicine, University of Cambridge
Research areas: Medicine · Infectious Diseases · SARS-CoV-2 and COVID-19 Research · T-cell and B-cell Immunology · Hepatitis C virus research
0000-0002-6837-8881
Employment
Education
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University of Oxford DPhil2018 - 2022
- 2015 - 2015
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University of Cambridge MB BChir2007 - 2010
- 2004 - 2007
Projects & Funding
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Bicarbonate transport and intracellular pH homeostasis as a checkpoint for T‑cell function in acidic tissues Wellcome2026 - 2031
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Effector Functions of MAIT cells in Response to Viral Infection and Vaccines Wellcome Trust2018 - 2022
Publications (44)
- CXCR3 on transferred T cells enables vaccine-boosted adoptive T-cell therapy in solid tumors Save
- Rapid glycolytic metabolism underpins mucosal-associated invariant T cell functional responses to innate cytokines. Save
- Dosing interval is a major factor determining the quality of T cells induced by SARS-CoV-2 mRNA and adenoviral vector vaccines Save
- MAIT and other innate-like T cells integrate adaptive immune responses to modulate interval-dependent reactogenicity to mRNA vaccines Save
- A case of disseminated autochthonous Cladophialophora bantiana infection in a renal transplant recipient in the UK Save
- Role of mucosal-associated invariant T cells in coronavirus disease 2019 vaccine immunogenicity Save
- A delicate balance between antibody evasion and ACE2 affinity for Omicron BA.2.75 Save
- Single-cell analysis of human MAIT cell transcriptional, functional and clonal diversity Save
- SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses Save
- Antibody escape of SARS-CoV-2 Omicron BA.4 and BA.5 from vaccine and BA.1 serum Save
- Comparison of two T cell assays to evaluate T cell responses to SARS-CoV-2 following vaccination in naïve and convalescent healthcare workers Save
- Comparison of two T-cell assays to evaluate T-cell responses to SARS-CoV-2 following vaccination in naïve and convalescent healthcare workers Save
- Evolution of long-term vaccine induced and hybrid immunity in healthcare workers after different COVID-19 vaccination regimens: a longitudinal observational cohort study Save
- Further antibody escape by Omicron BA.4 and BA.5 from vaccine and BA.1 serum Save
- Human MAIT cells show clonal diversity but transcriptional and functional homogeneity Save
- Impaired humoral and cellular response to primary COVID-19 vaccination in patients less than 2 years after allogeneic bone marrow transplant Save
- Potent cross-reactive antibodies following Omicron breakthrough in vaccinees Save
- T-cell and antibody responses to first BNT162b2 vaccine dose in previously infected and SARS-CoV-2-naive UK health-care workers: a multicentre prospective cohort study Save
- Adenovirus vectors activate Vδ2+ γδT cells in a type I interferon-, TNF-, and IL-18-dependent manner. Save
- Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses Save