Indrajit Srivastava
Texas Tech University, University of Illinois System, University of Illinois at Urbana Champaign, University of Illinois Urbana-Champaign
Research areas: Materials Science · Materials Chemistry · Luminescence and Fluorescent Materials · Nanoplatforms for cancer theranostics · Carbon and Quantum Dots Applications
0000-0002-6864-0202
About
Indrajit leads the Srivastava Lab in the Department of Mechanical & Aerospace Engineering at Texas Tech University within the Edward E. Whitacre Jr. College of Engineering. The lab is located in the newly constructed Maddox Engineering Research Center. The Srivastava Lab develops advanced biomaterials inspired by nature and guided by nanoengineering design principles. Its research focuses on translating these innovations into diagnostic platforms and surgical interventions for diseases including cancer and cardiovascular disorders. The lab is currently supported by multiple grants from the American Heart Association, including a Career Development Award to pioneer NIR-II hypoxia probes for diagnosing pulmonary embolism, and National Institute of Health (R35 MIRA) to develop NIR-II nanofluorophores for generalizable bioimaging across multiple disease contexts. Additional support comes from the Cancer Prevention & Research Institute of Texas to develop protein-complexed cyanine nanofluorophores for liver cancer surgery, and from the Robert A. Welch Foundation to investigate more fundamental insights into a “ping-pong” afterglow dynamics within self-assembled polymeric molecular cubes.
Employment
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Texas Tech University Assistant Professor2023 - Present
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University of Illinois System Postdoctoral Research Associate2020 - 2022
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University of Illinois at Urbana-Champaign Graduate Research Assistant2015 - 2019
Education
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University of Illinois at Urbana Champaign Ph.D.2017 - 2020
- 2015 - 2017
- 2011 - 2015
Projects & Funding
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Hypoxia-Activatable NIR-II Nanoprobes for Early Detection and Precision Treatment of Pulmonary Embolism American Heart Association2026 - 2029
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Albumin-Complexed Cyanine-Based NIR Afterglow Nanoprobes for Image-Guided Cancer Surgery Cancer Prevention and Research Institute of Texas2026 - 2028
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Design Maps Linking Polymer Architecture and Pharmacokinetics: A Platform for Generalizable Bioimaging US National Institutes of Health2026 - 2031
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Platelet-Mimicking NIR Afterglow Nanoprobes for Precise Early Detection of Atherosclerotic Plaques American Heart Association2025 - 2026
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'Ping-Pong' Afterglow Luminescence in Self-Assembled Molecular Cubes The Robert A. Welch Foundation2025 - 2026
Publications (49)
- Anatomically Programmable and Optically Tunable 3D-Bioprinted Tumor-Mimicking Phantoms for Quantitative Nanofluorophore Benchmarking Save
- Biomineralized SERS Nanotags Encode Biomolecular Identity into Machine Learning-Resolvable Fingerprints Save
- Architecture-Dependent Stability, Cellular Uptake, and Redox Modulation of Poly(p-Coumaric Acid) Hybrid Nanoparticles for Ovarian Carcinoma Intervention Save
- Unsymmetric Heptamethine Cyanines as a General Strategy to Construct Nonaggregating Fluorophores for Biomedical Imaging Save
- Rational Design and Development of Organic Afterglow Nanoparticles for Image‐Guided Interventions Save
- Biomineralized Surface-Enhanced Raman Scattering Nanotags Enable Machine Learning-Based Differentiation of Biomolecular Signatures Save
- Modular Albumin-Chaperoned NIR-II Nanofluorophores Enables Pan-Ovarian Cancer Imaging Across Multiscale Tumor Models Save
- Architecture-Dependent Stability, Cellular Uptake, and Redox Modulation of Poly(p-Coumaric Acid) Hybrid Nanoparticles for Ovarian Carcinoma Intervention Save
- Ultrabright NIR-II Nanoprobes for Ex Vivo Bioimaging: Protein Nanoengineering Meets Molecular Engineering Save
- Multivariable Design of a Minimalist Conjugated Polymer Nanoparticle with Bright NIR‐II Emission Save
- Unsymmetrical Heptamethine Cyanines Prevent Aggregation Save
- Unsymmetrical Heptamethine Cyanines Prevent Aggregation Save
- Ultrabright NIR-II Nanoprobes for Ex Vivo Bioimaging: Protein Nanoengineering Meets Molecular Engineering Save
- Surface‐Enhanced Raman Scattering Nanotags: Design Strategies, Biomedical Applications, and Integration of Machine Learning Save
- Surface-Enhanced Raman Spectroscopy for Biomedical Applications: Recent Advances and Future Challenges Save
- 3D Tumor-Mimicking Phantom Models for Assessing NIR I/II Nanoparticles in Fluorescence-Guided Surgical Interventions Save
- Rational Design of NIR‐II Emitting Conjugated Polymer Derived Nanoparticles for Image‐Guided Cancer Interventions Save
- Near‐Infrared Afterglow Luminescence Amplification via Albumin Complexation of Semiconducting Polymer Nanoparticles for Surgical Navigation in Ex Vivo Porcine Models Save
- Effect of Polymer and Cell Membrane Coatings on Theranostic Applications of Nanoparticles: A Review Save
- Biomimetic-Membrane-Protected Plasmonic Nanostructures as Dual-Modality Contrast Agents for Correlated Surface-Enhanced Raman Scattering and Photoacoustic Detection of Hidden Tumor Lesions Save