Saurabh Kumar

About

My name is Saurabh, and I am completed my PhD at L V Prasad Eye Institute, India. My doctoral research focuses on “understanding the role of altered lipid metabolism and signalling under oxidative stress in retinopathy of prematurity (ROP).” My research explores the interplay between lipid metabolism and cellular stress responses in retinal health and disease. I am particularly interested in how disruptions in metabolic pathways contribute to retinal neurodegeneration and conditions such as Retinopathy of Prematurity (ROP).

My current projects include:

Investigating the role of phospholipids and sphingolipids in retinal angiogenesis and neuronal survival.
Examining the impact of ceramide toxicity on Müller glial cells and retinal neurons.
Utilizing machine learning-assisted frameworks for designing biosensors to diagnose and monitor retinal diseases.

Beyond my research, I am committed to advancing scientific knowledge in developing countries and raising awareness of how lipid metabolism affects overall health.

Employment

• University of Rochester Medical Center Postdoctoral Research Associate
  2025 - Present
• L V Prasad Eye Institute Senior Research Fellow (DBT, PhD)
  2022 - 2025
• L V Prasad Eye Institute Junior Research Fellow (PhD)
  2020 - 2022
• LV Prasad Eye Institute Junior Research Fellow (DST-IMPRINT Project)
  2019 - 2020
• University of Hyderabad Project Assosciate
  2019 - 2019

Education

• L V Prasad Eye Institute Doctor of Philosophy
  2020 - 2025
• University of Hyderabad MSc (Molecular Microbiology)
  2017 - 2019

Projects & Funding

Projects & funding information is unavailable.

Publications (11)

• Development of a Disposable Chemiresistive Biochip for Tear-Based Retinopathy of Prematurity Diagnosis: Early Screening and Risk Prediction
  IEEE Sensors Journal 2026 DOI: 10.1109/JSEN.2025.3645254
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• Role of Calcium in the Regulation of Chronic Stress-Induced Progression of Stress Granule Assembly in N2a Cells
  ACS Chemical Neuroscience 2025 DOI: 10.1021/acschemneuro.5c00588
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• Arachidonic acid metabolism regulates the development of retinopathy of prematurity among preterm infants
  Journal of Neurochemistry 2024 DOI: 10.1111/jnc.16190
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• Predictive markers for retinopathy of prematurity development and progression
  Investigative Ophthalmology & Visual Science 2024
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• Integrative Metabolomics and Transcriptomics Identify Lipid Metabolism as a Key Mediator in Retinopathy of Prematurity
  Investigative Ophthalmology & Visual Science 2023
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• Protocol and Methods Applicable to Retinal Vascular Diseases
  Methods in Molecular Biology 2023 DOI: 10.1007/978-1-0716-2966-6_6
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• Tear-based MMP-9 detection: A rapid antigen test for ocular inflammatory disorders using vanadium disulfide nanowires assisted chemi-resistive biosensor
  Analytica Chimica Acta 2023 DOI: 10.1016/j.aca.2023.341281
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• Three-Dimensional Tracking of Intracellular Calcium and Redox State during Real-Time Control in a Hypoxic Gradient in Microglia Culture: Comparison of the Channel Blocker and Reoxygenation under Ischemic Shock
  ACS Chemical Neuroscience 2023 DOI: 10.1021/acschemneuro.2c00807
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• Detailed investigation on the role of lipid metabolizing enzymes in the pathogenesis of retinopathy of prematurity among preterm infants
  bioRxiv 2022 DOI: 10.1101/2022.05.13.491711
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• Molecular Mechanisms in the Pathogenesis of Retinopathy of Prematurity (ROP)
  Genetics of Ocular Diseases 2022 DOI: 10.1007/978-981-16-4247-0_9
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