David J Ahern

Employment

• University of Oxford

Education

Education history is unavailable.

Projects & Funding

Projects & funding information is unavailable.

Publications (17)

• Divergent granulopoiesis at extramedullary sites safeguards antibacterial host defense
  Science Immunology 2026 DOI: 10.1126/sciimmunol.adw7077
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• Single cell spatial analysis reveals inflammatory foci of immature neutrophil and CD8 T cells in COVID-19 lungs.
  Nature communications 2023 DOI: 10.1038/s41467-023-42421-0
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• Mass cytometry as a tool in target validation and drug discovery.
  Methods in enzymology 2023 DOI: 10.1016/bs.mie.2023.07.006
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• Myeloid CD40 deficiency reduces atherosclerosis by impairing macrophages' transition into a pro-inflammatory state.
  Cardiovascular research 2023 DOI: 10.1093/cvr/cvac084
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• A blood atlas of COVID-19 defines hallmarks of disease severity and specificity
  2021 DOI: 10.1101/2021.05.11.21256877
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• Activated Regulatory T-Cells, Dysfunctional and Senescent T-Cells Hinder the Immunity in Pancreatic Cancer
  Cancers 2021 DOI: 10.3390/cancers13081776
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• ROS producing immature neutrophils in Giant Cell Arteritis are linked to vascular pathologies
  JCI Insight 2020 DOI: 10.1172/jci.insight.139163
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• Activated regulatory T-cells, dysfunctional and senescent T-cells dominate the microenvironment of pancreatic cancer
  2020 DOI: 10.1101/2020.06.20.163071
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• Histone H3K27me3 demethylases regulate human Th17 cell development and effector functions by impacting on metabolism.
  Proceedings of the National Academy of Sciences of the United States of America 2020 DOI: 10.1073/pnas.1919893117
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• Structural Remodeling of the Human Colonic Mesenchyme in Inflammatory Bowel Disease.
  Cell 2018 DOI: 10.1016/j.cell.2018.08.067
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• Immune cell census in murine atherosclerosis: cytometry by time of flight illuminates vascular myeloid cell diversity.
  Cardiovascular research 2018 DOI: 10.1093/cvr/cvy109
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• Balance between activating NKG2D, DNAM-1, NKp44 and NKp46 and inhibitory CD94/NKG2A receptors determine natural killer degranulation towards rheumatoid arthritis synovial fibroblasts.
  Immunology 2014 DOI: 10.1111/imm.12271
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• CXCR4 and vascular cell adhesion molecule 1 are key chemokine/adhesion receptors in the migration of cytokine-activated T cells.
  Arthritis and rheumatism 2012 DOI: 10.1002/art.34394
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• Blockade of NKG2D ameliorates disease in mice with collagen-induced arthritis: a potential pathogenic role in chronic inflammatory arthritis.
  Arthritis and rheumatism 2011 DOI: 10.1002/art.30460
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• The role of Natural Killer cells in the pathogenesis of rheumatoid arthritis: major contributors or essential homeostatic modulators?
  Immunology letters 2010 DOI: 10.1016/j.imlet.2010.11.001
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• Chemokine responsiveness of CD4+ CD25+ regulatory and CD4+ CD25- T cells from atopic and nonatopic donors.
  Allergy 2009 DOI: 10.1111/j.1398-9995.2008.01962.x
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• Regulatory T cells as a target for induction of immune tolerance in allergy.
  Current opinion in allergy and clinical immunology 2005 DOI: 10.1097/01.all.0000191239.20632.ab
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