Aditya Trivedi

About

Aditya Trivedi is a researcher at the Centre for Advanced Technologies, Adam Mickiewicz University in Poznań, Poland, specializing in enzymology, protein biochemistry, and molecular genetics. His research focuses on the functional characterization of proteases, with a current emphasis on the DPPIV family and their roles in protein and peptide processing within both animal model systems and human biology. In a recent publication, he demonstrated, for the first time, the tripeptidyl peptidase activity of the C. elegans enzyme DPF-3 and its human homolog, DPP4, work that revises classical definitions of substrate specificity and expands understanding of protease functions in genome stability, immune response, and therapeutic inhibitor design.​

Aditya has a strong background in the development and application of biochemical assays, protein expression, purification, and biochemical kinetics. His collaborative projects include in vivo proteomics, structural biology (notably structural alignment and comparative modeling), and computational screening for substrate identification. His contributions are supported by grants from the National Science Center (NCN) in Poland.

Employment

• Adam Mickiewicz University in Poznań Postdoctoral Researcher
  2025 - Present
• Central Drug Research Institute Project Assistant
  2018 - 2019

Education

Education history is unavailable.

Projects & Funding

Projects & funding information is unavailable.

Publications (6)

• The Caenorhabditis elegansDPF‐3 and human DPP4 have tripeptidyl peptidase activity
  FEBS Letters 2026 DOI: 10.1002/1873-3468.70219
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• Corticosteroid Prednisolone and flavonoid Chrysin as drug candidates against SARS-CoV-2 replication: Computational and experimental findings
  Microbial Pathogenesis 2025 DOI: 10.1016/j.micpath.2025.107923
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• Psoralidin acts as a dual protease inhibitor against PLpro and Mpro of SARS‐CoV‐2
  The FEBS Journal 2025 DOI: 10.1111/febs.17380
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• Identification of a novel inhibitor of SARS-CoV-2 main protease: an in silico, biochemical, and cell-based approach
  VirusDisease 2024
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• Identification of a novel inhibitor of SARS-CoV-2 main protease: an in silico, biochemical, and cell-based approach
  The FEBS Journal 2023 DOI: 10.1111/FEBS.16947
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• Biochemical and Biophysical Characterisation of the Hepatitis E Virus Guanine-7-Methyltransferase
  Molecules 2022 DOI: 10.3390/MOLECULES27051505
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