Nicolas Altemose

About

Assistant Professor of Genetics at Stanford University

Employment

• Stanford University Assistant Professor
  2023 - Present
• University of California Berkeley Postdoctoral Fellow
  2021 - 2023

Education

• University of California, Berkeley PhD
  2015 - 2021
• University of Oxford DPhil
  2011 - 2016
• Duke University B.S. Biology: Genomics
  2007 - 2011

Projects & Funding

Projects & funding information is unavailable.

Publications (50)

• A practical guide to studying genome function using single-molecule genomics
  Nature Reviews Molecular Cell Biology 2026 DOI: 10.1038/s41580-026-01017-4
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• Single-molecule variation in telomeric sequence and structure across humans
  2026 DOI: 10.64898/2026.05.01.722200
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• Haplotype-resolved centromeric chromatin organization from a complete diploid human genome.
  bioRxiv : the preprint server for biology 2026 DOI: 10.64898/2026.03.27.714900
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• Heterochromatin boundaries maintain centromere position, size and number.
  Nature structural & molecular biology 2025 DOI: 10.1038/s41594-025-01706-2
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• Integrated analysis of multimodal long-read epigenetic assays
  2025 DOI: 10.1101/2025.11.09.687458
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• A telomere-to-telomere map of somatic mutation burden and functional impact in cancer.
  bioRxiv : the preprint server for biology 2025 DOI: 10.1101/2025.10.10.681725
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• A complete diploid human genome benchmark for personalized genomics.
  bioRxiv : the preprint server for biology 2025 DOI: 10.1101/2025.09.21.677443
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• DNA methylation influences human centromere positioning and function.
  Nature genetics 2025 DOI: 10.1038/s41588-025-02324-w
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• NKX2-1 drives neuroendocrine transdifferentiation of prostate cancer via epigenetic and 3D chromatin remodeling.
  Nature genetics 2025 DOI: 10.1038/s41588-025-02265-4
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• DiMeLo-cito: a one-tube protocol for mapping protein-DNA interactions reveals CTCF bookmarking in mitosis.
  bioRxiv : the preprint server for biology 2025 DOI: 10.1101/2025.03.11.642717
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• Integrating Single-Molecule Sequencing and Deep Learning to Predict Haplotype-Specific 3D Chromatin Organization in a Mendelian Condition
  2025 DOI: 10.1101/2025.02.26.640261
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• Mapping protein–DNA interactions with DiMeLo-seq
  Nature Protocols 2024 DOI: 10.1038/s41596-024-01032-9
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• Enhancing transcription-replication conflict targets ecDNA-positive cancers.
  Nature 2024 DOI: 10.1038/s41586-024-07802-5
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• Human Satellite 3 DNA encodes megabase-scale transcription factor binding platforms
  2024 DOI: 10.1101/2024.10.22.616524
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• The complete sequence of a human Y chromosome
  Arang Rhie, Sergey Nurk, Monika Čechová

  +84 more

  • Savannah J. Hoyt
  • Dylan J. Taylor
  • Nicolas Altemose
  • Paul W. Hook
  • Sergey Koren
  • +79 more
  Nature 2023 DOI: 10.1038/s41586-023-06457-y
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• The complete sequence of a human Y chromosome
  2022 DOI: 10.1101/2022.12.01.518724
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• Mapping protein-DNA interactions with DiMeLo-seq
  2022 DOI: 10.1101/2022.07.03.498618
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• A classical revival: Human satellite DNAs enter the genomics era
  SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY 2022 DOI: 10.1016/j.semcdb.2022.04.012
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• DiMeLo-seq: a long-read, single-molecule method for mapping protein–DNA interactions genome wide
  Nature Methods 2022 DOI: 10.1038/s41592-022-01475-6
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• A classical revival: Human satellite DNAs enter the genomics era
  2022 DOI: 10.20944/preprints202202.0009.v2
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