VB
Vidhya Bharathi
University of Miami Hospital, Mayo Clinic in Florida, Indian Institute of Technology Hyderabad, Government College of Technology
0000-0002-7232-523X
Employment
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University of Miami Hospital Assistant Scientist2026 - Present
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Mayo Clinic in Florida Research Fellow2022 - 2026
Education
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Indian Institute of Technology Hyderabad PhD student2016 - 2021
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Indian Institute of Technology Hyderabad Post graduate (M.Tech Medical Biotechnology)2014 - 2016
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Government College of Technology Under-graduate (B.Tech Industrial Biotechnology)2010 - 2014
Projects & Funding
Projects & funding information is unavailable.
Publications (17)
- TDP-43-mediated alternative polyadenylation is associated with a reduction in VPS35 and VPS29 expression in frontotemporal dementia Save
- TDP-43 nuclear loss in FTD/ALS causes widespread alternative polyadenylation changes Save
- TDP-43 dysregulation of polyadenylation site selection is a defining feature of RNA misprocessing in amyotrophic lateral sclerosis and frontotemporal dementia Save
- Enhanced in vitro aggregation, but not phase separation, of TDP-43 and its C-terminal fragments generates intrinsic deep-blue autofluorescence Save
- Enhancedin vitroaggregation, but not phase separation, of TDP-43 and its C-terminal fragments generate deep-blue autofluorescence Save
- TMEM106B core deposition associates with TDP-43 pathology and is increased in risk SNP carriers for frontotemporal dementia Save
- Elevated constitutive expression of Hsp40 chaperone Sis1 reduces TDP-43 aggregation-induced oxidative stress in Ire1 pathway dependent-manner in yeast TDP-43 proteinopathy model of amyotrophic lateral sclerosis Save
- TDP-43 proteinopathy mechanisms from non-mammalian model systems Save
- Amyloid-like aggregation of bovine serum albumin at physiological temperature induced by cross-seeding effect of HEWL amyloid aggregates Save
- Zn2+ modulates in vitro phase separation of TDP-432C and mutant TDP-432C-A315T C-terminal fragments of TDP-43 protein implicated in ALS and FTLD-TDP diseases Save