Dr. Sarfaraz Alam

About

I’m a researcher and academician specializing in Bioinformatics, Computational Biology, and Biomedical Informatics, with over ten years of experience in computer-aided drug design (CADD), cheminformatics, systems pharmacology, and pharmacometrics. My work focuses on integrating computational modeling with experimental validation to accelerate the drug discovery process. Currently, I serve as an Assistant Professor at the Institute of Advanced Research, where I’m actively involved in interdisciplinary research and mentoring scholars in computational Modelling, Biomedical Informatics, drug design and discovery. I’ve been fortunate to receive several prestigious grants, including the Mitacs Industrial Postdoctoral Fellowship (MITACS, Canada) and the Young Scientist Fellowship (ICMR, India).

Please visit my Lab @ [https://sarfarazalam408.wixsite.com/the-computational-dr]

Employment

• University of Waterloo
  2019 - Present
• Indian Institute of Science Education and Research Institutional Post-Doc Fellow
  2018 - Present
• CSIR - Central Institute of Medicinal and Aromatic Plants Young Scientist Fellow
  2015 - 2018
• Institute of Advance Research Assistant Professor

Education

• Academy of Scientific and Innovative Research PhD
  2013 - 2018

Projects & Funding

Projects & funding information is unavailable.

Publications (36)

• In Vivo and In Silico Pharmacokinetics Studies on Coumarinolignoid Cliv-92: Unraveling its Effect on Rifampicin-Induced Hepatic Damage
  Current Topics in Medicinal Chemistry 2025 DOI: 10.2174/0115680266329609241223114551
  +Save
• Pharmacophore & QSAR Guided Design, Synthesis, Pharmacokinetics and In vitro Evaluation of Curcumin Analogs for Anticancer Activity
  Current Medicinal Chemistry 2024 DOI: 10.2174/0929867330666230428162720
  +Save
• Pharmacophore-based virtual screening, molecular docking, and molecular dynamics studies for the discovery of novel FLT3 inhibitors
  Journal of Biomolecular Structure and Dynamics 2023 DOI: 10.1080/07391102.2022.2123403
  +Save
• In-silico studies and wet lab validation of Camptothecin derivatives for anti-cancer activity against liver (HepG2) and lung (A549) cancer cell lines.
  Current topics in medicinal chemistry 2021 DOI: 10.2174/1568026621666210426124719
  +Save
• Antihypertensive Effect of a Novel Angiotensin II Receptor Blocker Fluorophenyl Benzimidazole: Contribution of cGMP, Voltage-dependent Calcium Channels, and BKCa Channels to Vasorelaxant Mechanisms.
  Frontiers in pharmacology 2021 DOI: 10.3389/fphar.2021.611109
  +Save
• Detection of Natural Inhibitors against Human Liver Cancer Cell Lines through QSAR, Molecular Docking and ADMET Studies
  Current Topics in Medicinal Chemistry 2021 DOI: 10.2174/1568026620666201204155830
  +Save
• Synthesis of Novel Hybrids of Thiazolidinedione-Triazoles as Potential Lipase and a-Glucosidase Inhibiting Agents
  Indian Journal of Heterocyclic Chemistry 2021
  +Save
• In vitro antiproliferative activity of glabridin derivatives and their in silico target identification
  Natural Product Research 2020 DOI: 10.1080/14786419.2018.1530228
  +Save
• Brevifoliol and its Analogs: A New Class of Antitubercular Agents
  Current Topics in Medicinal Chemistry 2020 DOI: 10.2174/1568026620666200528155236
  +Save
• A Small Molecule Inhibitor Prevents Insulin Fibrillogenesis and Preserves Activity
  Molecular Pharmaceutics 2020 DOI: 10.1021/acs.molpharmaceut.9b01080
  +Save