SG
Sonia Guha
University of Miami Health System, University of California, Los Angeles, University of Pennsylvania
0000-0002-7585-8381
Employment
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University of Miami Health System Staff Research Scientist2025 - Present
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University of California, Los Angeles Postdoctoral Fellow/Staff Research Scientist2012 - 2023
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University of Pennsylvania Postdoctoral Researcher2008 - 2012
Education
Education history is unavailable.
Projects & Funding
Projects & funding information is unavailable.
Publications (13)
- Autism Spectrum Disorders and Purinergic Signaling: A Systematic Review of Emerging Insights from Preclinical Studies Save
- Decreased CREB phosphorylation impairs embryonic retinal neurogenesis in the Oa1-/- mouse model of Ocular albinism Save
- Polarized Cytokine Release Triggered by P2X7 Receptor from Retinal Pigmented Epithelial Cells Dependent on Calcium Influx. Save
- Assays for Intracellular Cyclic Adenosine Monophosphate (cAMP) and Lysosomal Acidification. Save
- The P2Y12 Receptor Antagonist Ticagrelor Reduces Lysosomal pH and Autofluorescence in Retinal Pigmented Epithelial Cells From the ABCA4-/- Mouse Model of Retinal Degeneration. Save
- Approaches for detecting lysosomal alkalinization and impaired degradation in fresh and cultured RPE cells: evidence for a role in retinal degenerations. Save
- Rescue of compromised lysosomes enhances degradation of photoreceptor outer segments and reduces lipofuscin-like autofluorescence in retinal pigmented epithelial cells. Save
- Lysosomal alkalinization, lipid oxidation, and reduced phagosome clearance triggered by activation of the P2X7 receptor. Save
- Acidic nanoparticles are trafficked to lysosomes and restore an acidic lysosomal pH and degradative function to compromised ARPE-19 cells. Save
- Stimulation of the D5 dopamine receptor acidifies the lysosomal pH of retinal pigmented epithelial cells and decreases accumulation of autofluorescent photoreceptor debris. Save