Sriram Rathnakumar

About

I am a biomedical researcher with postdoctoral experience in innovative diagnostic technologies, specializing in plasmonic fiber-optic immunoassays and nucleic-acid–based point-of-care platforms. I have worked on a Pfizer-funded industrial project, where I developed U-bent fiber optic plasmonic sandwich immunoassays for ultrasensitive antigen detection through advanced surface biofunctionalization and gold nanoparticle conjugation strategies. Currently, I am working on a multiplex nucleic acid biosensor platform for the differential diagnosis of MDR/XDR Tuberculosis, integrating primer design, biomarker analysis, and rolling circle amplification using clinical samples in collaboration with ICMR–NIRT. I bring a strong track record of high-impact publications, grant writing, good leadership abilities and strong interdisciplinary collaboration, with a deep passion for advancing biomedical research through cutting-edge analytical techniques and transformative point-of-care technologies.

Employment

• Indian Institute of Technology Madras Project Research Scientist II
  2025 - Present
• Indian Institute of Technology Madras Post Doctoral Researcher
  2024 - 2025
• Sri Sathya Sai Institute of Higher Learning Doctoral Research Scholar
  2017 - 2023

Education

Education history is unavailable.

Projects & Funding

Projects & funding information is unavailable.

Publications (8)

• Clopidogrel modulate deregulated metabolic pathways in cuprizone fed mice model of Multiple Sclerosis
  3 Biotech 2026 DOI: 10.1007/s13205-026-04715-0
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• Emerging Trends in Optical and Magnetic Sensing for Biomolecular Detection
  Engineering Nanoparticles for Biomedical Applications 2026 DOI: 10.1002/9783527844791.ch14
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• Tecoma stans Floral Extract-Based Biosynthesis for Enhanced Surface Plasmon-Coupled Emission and a Preliminary Study on Fluoroimmunoassay
  Analytical Chemistry 2024 DOI: 10.1021/acs.analchem.3c01441
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• Integrated clinical and metabolomic analysis of dengue infection shows molecular signatures associated with host-pathogen interaction in different phases of the disease
  Metabolomics 2023 DOI: 10.1007/s11306-023-02011-z
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• Electrospun PVA nanofibers doped with titania nanoparticles in plasmon-coupled fluorescence studies: An eco-friendly and cost-effective transition from 2D nano thin films to 1D nanofibers
  MRS Communications 2023 DOI: 10.1557/s43579-023-00342-5
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• Integrated Omic Analysis Delineates Pathways Modulating Toxic TDP-43 Protein Aggregates in Amyotrophic Lateral Sclerosis
  Cells 2023 DOI: 10.3390/cells12091228
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• Integrated multi-omics analysis of Huntington disease identifies pathways that modulate protein aggregation
  Disease Models & Mechanisms 2022 DOI: 10.1242/dmm.049492
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• Plasmon-Coupled Silver Nanoparticles for Mobile Phone-Based Attomolar Sensing of Mercury Ions
  ACS Applied Nano Materials 2021 DOI: 10.1021/acsanm.1c01347
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