Sweta Iyer

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Publications (14)

• Structure of the BAK-activating antibody 7D10 bound to BAK reveals an unexpected role for the α1-α2 loop in BAK activation
  Cell Death & Differentiation 2022 DOI: 10.1038/s41418-022-00961-w
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• Structure of detergent-activated BAK dimers derived from the inert monomer
  Molecular Cell 2021 DOI: 10.1016/j.molcel.2021.03.014
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• Robust autoactivation for apoptosis by BAK but not BAX highlights BAK as an important therapeutic target
  Cell Death & Disease 2020 DOI: 10.1038/s41419-020-2463-7
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• Avoiding adsorption of Bcl-2 proteins to plasticware is important for accurate quantitation
  Cell Death & Differentiation 2019 DOI: 10.1038/s41418-019-0284-y
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• BAX Activation: Mutations Near Its Proposed Non-canonical BH3 Binding Site Reveal Allosteric Changes Controlling Mitochondrial Association
  Cell Reports 2019 DOI: 10.1016/j.celrep.2019.03.040
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• Probing BAK and BAX Activation and Pore Assembly with Cytochrome c Release, Limited Proteolysis, and Oxidant-Induced Linkage
  Methods in Molecular Biology 2019 DOI: 10.1007/978-1-4939-8861-7_14
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• Ensemble Properties of Bax Determine Its Function
  Structure 2018 DOI: 10.1016/j.str.2018.07.006
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• Pore formation by dimeric Bak and Bax: an unusual pore?
  Philosophical Transactions of the Royal Society B: Biological Sciences 2017 DOI: 10.1098/rstb.2016.0218
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• Epigenetic control of mitochondrial cell death through PACS1-mediated regulation of BAX/BAK oligomerization
  Cell Death & Differentiation 2017 DOI: 10.1038/cdd.2016.119
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• Disordered clusters of Bak dimers rupture mitochondria during apoptosis.
  eLife 2017 DOI: 10.7554/elife.19944
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