Prof. Dr. Assem Barakat
King Saud University, Pharos University in Alexandria, Politecnico di Milano, Alexandria University
Research areas: Chemistry · Inorganic Chemistry · Crystal structures of chemical compounds · Crystallography and molecular interactions · Crystal Structures and Properties
0000-0002-7885-3201
About
Professor Assem Barakat is a Distinguished Full Professor of Organic Chemistry at King Saud University, Riyadh, Saudi Arabia. He earned his Ph.D. in 2010 through an elite international consortium involving Politecnico di Milano (Italy), ETH Zurich (Switzerland), and the University of Stuttgart (Germany). His pioneering research stands at the forefront of therapeutic discovery, with a principal focus on the rational design of novel anticancer agents. He is internationally recognized for his work on protein-protein interaction inhibitors, particularly targeting the p53-MDM2 pathway, alongside the development of small molecules inhibiting key oncological targets (HER2, CDK2, PI3K) and other therapeutic areas. A scholar of profound influence, Professor Barakat has authored over 330 scientific publications and holds five US patents. His scientific eminence is reflected by his consistent inclusion in the Stanford University/Elsevier list of the world's top 2% most-cited scientists (2020-2025). His distinguished career has been honored with the Arab Chemistry Award (2016) and the IAAM Scientist Medal (2020). Beyond his research, he is a devoted mentor to the next generation of scientists, having supervised the successful completion of 13 Master's and four Ph.D. theses.
Employment
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King Saud University Full Professor2021 - Present
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King Saud University Associate Professor2017 - 2021
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King Saud University Assistant Professor2011 - 2017
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Pharos University in Alexandria Lecturer of Organic Chemistry2010 - 2011
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Alexandria University Chemist2003 - 2010
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Pharco Pharmaceutical Company Chemist2003 - 2003
Education
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Politecnico di Milano PhD in Industrial Chemistry and Chemical Engineering2007 - 2010
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Alexandria University Graduate courses in Organic Chemistry for MSc. degree2003 - 2004
- 1998 - 2002
Projects & Funding
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Research Group Fund-257 Deanship of Scientific Research, King Saud University
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NPST Project No. 14-BIO128-02 National Plan for Science, Technology and Innovation
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COVID-19 research Project Dr. Sulaiman Al Habib Medical Services Group Company
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Grant no. (RGP-1443-0040). Deanship of Scientific Research, Princess Nourah Bint Abdulrahman University
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RSP-2021/64; RSP-2020/64; RSP-2019/64 King Saud University
Publications (341)
- A novel μ-iodo dinuclear Cu(I) complex based on Schiff base thiazole type ligand; synthesis, structural analysis, and biological evaluation Save
- Zn(II) and Cd(II) carboxylate complexes of s-triazine pincer ligand: Crystal structure, Hirshfeld analysis, DFT calculations, and biological studies Save
- Photocatalytic activation of [3+2] cycloaddition for the sustainable and stereoselective assembly of spirooxindoles combined with MEDT mechanistic study Save
- Synthesis, Crystal Structure, DFT, Hirshfeld Analysis, and Molecular Docking Studies of s‐Triazine‐Based Hg(II) Complexes as Promising Antimicrobial Candidates Save
- 2-aminothiophene Schiff bases: Synthesis, characterization, Hirshfeld surface analysis, and their biological implications Save
- Synthesis, X-ray diffraction, computational, biological, and molecular docking studies of Cu(II) and Ni(II) complexes containing N, O-donor ligands Save
- Indenoquinoxaline‐Based Spiro‐Heterocycles: Synthesis, Structural Characterization, MEDT Study, and Dual Inhibition of Kinase‐Related Enzymes EGFR and VEGFR2 Save
- New s‐Triazine–Hydrazone Hybrids Targeting EGFR: Design and Anticancer Activity Against A549 Lung Adenocarcinoma Save
- Triazine-based corrosion inhibitors: synthesis, significance, and emerging perspectives Save
- Synthesis of copper(II) and cobalt(II) complexes with bidentate s-triazine ligand bearing pyrazolyl moiety; X-ray structural studies and antimicrobial evaluation Save
- Synthesis, Structural Characterization, Biological Activity, and DFT Studies of Cd(II) Complexes With Tridentate s‐Triazine Ligands Save
- Synthesis, X-ray structure, Hirshfeld analysis, molecular docking and anticancer evaluation of 1,2,3-triazole-pyrazolopyrimidine hybrids Save
- Synthesis, molecular structure investigations, hirshfeld analysis, non-linear optical properties of Hg(II) pincer complexes based on s-triazine ligands Save
- Water‐Soluble Silver Coordination Polymers Constructed From Bridging Pyrazine Ligands: Syntheses, X‐Ray Structures, Anticancer, and Antimicrobial Investigations Save
- Mn(II), Co(II), and Ni(II)-isothiocyanato complexes of s-triazine based ligand with promising cytotoxic and antimicrobial properties; synthesis, X-ray structure, and theoretical studies Save
- Catalyst free regiospecific amination, structural elucidation, and potential utilization of pyran-2,4‑dione derivatives as novel antimicrobial agents Save
- Self‐Assembled d10‐Metal (Cd(II), Zn(II), and Ag(I)) Complexes of Amino bis‐Pyrazolo‐s‐Triazine Pincer Ligand With Promising Anticancer and Antimicrobial Activities Save
- Nanoformulations for Hydrazones; Synthesis, Characterization, Parasitology, and Histopathology Investigations Save
- Synthesis of Marine-Inspired Multifaceted DNA Damaging Spirooxindoles Combating NSCLC and Associated Bacterial Infection Save
- A new Ag(I) complex based on asymmetric azine-type ligand as a promising anticancer agent: Synthesis, X-ray structure, and DFT calculations Save