MG
Shaik Mahammad Ghouse
National Institute of Pharmaceutical Education and Research, Jawaharlal Nehru Technological University Anantapur
0000-0002-7907-4250
About
As a PhD Scholar at NIPER Hyderabad, I am passionate about designing novel inhibitors for drug discovery, using organic synthesis and computational techniques. I have designed and synthesized several new classes of small molecule inhibitors for validated targets, and analyzed their structure-activity relationships (SARs) using various spectroscopic and chromatographic methods. I have also performed in silico docking, molecular dynamics, and pharmacokinetic simulations to optimize the inhibitors' binding affinity, selectivity, and stability.
Employment
Employment history is unavailable.
Education
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National Institute of Pharmaceutical Education and Research PhD2018 - 2023
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National Institute of Pharmaceutical Education and Research M.S Pharm.2016 - 2018
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Jawaharlal Nehru Technological University Anantapur Bachelor of Pharmacy2012 - 2016
Projects & Funding
Projects & funding information is unavailable.
Publications (23)
- Identification of novel MmpL3 inhibitors using in silico methods: Virtual screening, rational design, and biological evaluation Save
- Synthesis and Biological Evaluation of Indole‐Benzene Sulfonamides as Carbonic Anhydrase II, IX, and XII Inhibitors Save
- Synthesis and biological evaluation of new 3-substituted coumarin derivatives as selective inhibitors of human carbonic anhydrase IX and XII Save
- Synthesis and Biological Evaluation of Diphenyl Ether‐Linked Quinolone Derivatives as Antibacterial Agents Save
- Small molecule inhibitors of NLRP3 inflammasome and GSK-3β in the management of traumatic brain injury: A review Save
- 6-Aminocoumarin oxime-ether/sulfonamides as selective hCA IX and XII inhibitors: Synthesis, evaluation, and molecular dynamics studies Save
- Design, synthesis, and structure–activity studies of new rhodanine derivatives as carbonic anhydrase II, IX inhibitors Save
- Microwave-assisted Cu(i)-catalyzed one-pot tandem synthesis of pyridoimidazole-fused quinolines as new antimycobacterial agents: DFT and ESI-HRMS study Save
- Oxiconazole Potentiates Gentamicin against Gentamicin-Resistant Staphylococcus aureus in Vitro and in Vivo Save
- Lipid nanoparticles in topical dermal drug delivery: Does chemistry of lipid persuade skin penetration? Save