Dr. Jinendiran Sekar
Lundquist Institute for Biomedical Innovation, Harbor-UCLA Medical Center, Cleveland Clinic Foundation, Madurai Kamaraj University, Bharathidasan University, Thiruvalluvar University
0000-0002-8044-1628
About
Dr. Jinendiran Sekar is a Research Scientist, Division of Infectious Diseases, The Lundquist Institute, Harbor-UCLA Medical Center who joined the Swidergall Lab in June 2023. He received his Ph.D. in Biotechnology from Madurai Kamaraj University, India, where his research focused on the effects of dietary probiotics on host immunity and resistance to bacterial infections, as well as the identification of novel anticancer and anti-inflammatory molecules derived from probiotic bacteria. He completed his postdoctoral training at the Division of Inflammation and Immunity, Lerner Research Institute, Cleveland Clinic, USA, where he investigated metabolic perturbations and their contribution to sarcopenia in conditions such as hyperammonemia and alcohol-associated liver disease. Dr. Sekar is passionate about translating scientific discoveries into therapeutic strategies for patients with chronic metabolic diseases. He has a strong curiosity about the intersection of immunometabolism and mucosal immunity, particularly during mucosal fungal infections. His long-term research goal is to develop a detailed mechanistic understanding of metabolic regulation in mucosal immunity in the context of diabetes-associated infectious complications. Ultimately, he aims to develop targeted therapies to reduce infection risk and improve the quality of life for people living with diabetes.
Employment
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Lundquist Institute for Biomedical Innovation, Harbor-UCLA Medical Center Postdoctoral Researcher2023 - Present
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Cleveland Clinic Foundation Postdoctoral Fellow2020 - 2023
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Central Institute of Brackishwater Aquaculture Young Professional-II2019 - 2019
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Madurai Kamaraj University School of Biotechnology Senior Research Fellow2017 - 2017
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Madurai Kamaraj University School of Biotechnology Junior Research Fellow2015 - 2017
Education
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Madurai Kamaraj University Ph. D.,2015 - 2019
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Bharathidasan University M. Sc.,2012 - 2014
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Thiruvalluvar University B. Sc.,2009 - 2012
Projects & Funding
Projects & funding information is unavailable.
Publications (23)
- Non-canonical IL‑22 receptor signaling remodels the oral mucosal barrier during Candida albicans immunosurveillance Save
- Sympathetic neurons control adaptive immunity in response to Streptococcus pneumoniae infection by regulating T cell and B cell effector function Save
- Inhibition of Candida albicans yeast-to-hypha transition and virulence by cyclic dipeptides derived from probiotic Aeromonas veronii V03 Save
- Insights into biosynthesis, regulation, and functional potentials of exopolysaccharide from Leptolyngbya sp. MKU-05. Save
- Metabolic imprinting drives epithelial memory during mucosal fungal infection Save
- L-Isoleucine reverses hyperammonemia-induced myotube mitochondrial dysfunction and post-mitotic senescence Save
- The intersection of HIF-1α, O-GlcNAc, and skeletal muscle loss in chronic obstructive pulmonary disease Save
- Peripheral blood mononuclear cell mitochondrial dysfunction in acute alcohol‐associated hepatitis Save
- Dysregulated cellular redox status during hyperammonemia causes mitochondrial dysfunction and senescence by inhibiting sirtuin‐mediated deacetylation Save
- Gene polymorphisms associated with heterogeneity and senescence characteristics of sarcopenia in chronic obstructive pulmonary disease Save