PRIYANKA MOHAPATRA

About

Currently working on a novel phytonanomedicinal approach for targeting Breast Cancer Stem Cells.
Disciplines: Cancer Biology, Nanotechnology.
Skills and expertise:
Cancer, Cancer Stem Cells, Nanomedicine, Drug delivery, Cancer Biomarkers, Cell Culture, Cell Signaling, Flow Cytometry, Apoptosis, Cell Proliferation, Epithelial-Mesenchymal Transition, Metastasis, Western Blot, RT-PCR, Translational Medicine, High-Performance Liquid Chromatography (HPLC), Dynamic light scattering (DLS), Scanning electron microscope (SEM), Atomic force microscopy (AFM), Transmission electron microscope (TEM), X-Ray Diffraction (XRD), Fourier transform infrared (FTIR), Immunofluorescence, Epigenetics, DNA methylation, Chromatin immunoprecipitation (ChIP) assay, In vivo pharmacokinetics, In vivo Biodistribution, IVIS Spectrum (2D & 3D Optical Imaging Systems), Histology, Immunohistochemistry, Zebrafish Xenograft, Nude mice Xenograft, In vivo metastatic models (orthotopic and lung metastatic models).

Employment

• Institute of Life Sciences PhD Scholar (Senior Research Fellow)
  2018 - Present

Education

• Annamalai University M.Sc.
  2015 - 2017
• Ravenshaw University B.Sc.
  2012 - 2015

Projects & Funding

Projects & funding information is unavailable.

Publications (17)

• In-vitro anticancer evaluation of newly designed and characterized tri/tetra-substituted imidazole congeners- maternal embryonic leucine zipper kinase inhibitors: Molecular docking and MD simulation approaches
  International Journal of Biological Macromolecules 2023 DOI: 10.1016/j.ijbiomac.2023.126084
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• Nimbolide-based nanomedicine inhibits breast cancer stem-like cells by epigenetic reprogramming of DNMTs-SFRP1-Wnt/β-catenin signaling axis
  Molecular Therapy - Nucleic Acids 2023 DOI: 10.1016/j.omtn.2023.102031
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• Phytochemical-Based Nanomedicine for Targeting Tumor Microenvironment and Inhibiting Cancer Chemoresistance: Recent Advances and Pharmacological Insights
  Molecular Pharmaceutics 2023 DOI: 10.1021/acs.molpharmaceut.3c00286
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• Design, synthesis, and in-silico study of chromen-sulfonamide congeners as potent anticancer and antimicrobial agents
  Journal of Molecular Structure 2023 DOI: 10.1016/j.molstruc.2023.135190
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• Nimbolide-encapsulated PLGA nanoparticles induces Mesenchymal-to-Epithelial Transition by dual inhibition of AKT and mTOR in pancreatic cancer stem cells
  Toxicology in Vitro 2022 DOI: 10.1016/j.tiv.2021.105293
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• Long-read 16S-seq reveals nasopharynx microbial dysbiosis and enrichment of Mycobacterium and Mycoplasma in COVID-19 patients: a potential source of co-infection
  Molecular Omics 2022 DOI: 10.1039/d2mo00044j
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• PEGylated Nanoparticles as a Versatile Drug Delivery System
  Nanoengineering of Biomaterials 2022 DOI: 10.1002/9783527832095.ch10
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• Biosynthesis of Rutin Trihydrate Loaded Silica Nanoparticles and Investigation of Its Antioxidant, Antidiabetic and Cytotoxic Potentials
  Journal of Inorganic and Organometallic Polymers and Materials 2022 DOI: 10.1007/s10904-022-02269-1
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• Phytochemical based nanomedicine: a panacea for cancer treatment, present status and future prospective
  OpenNano 2022 DOI: 10.1016/j.onano.2022.100055
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• Flavonoids for the treatment of breast cancer, present status and future prospective.
  Anti-cancer agents in medicinal chemistry 2022 DOI: 10.2174/1871520623666221024114521
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