TS
Tovah Shaw
University of Edinburgh, University of Manchester, King's College London, London School of Hygiene & Tropical Medicine, University of Cambridge
Research areas: Immunology and Microbiology · Immunology · T-cell and B-cell Immunology · Malaria Research and Control · Neuroinflammation and Neurodegeneration Mechanisms
0000-0002-8107-2836
Employment
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University of Edinburgh Lecturer in Immunology2023 - Present
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University of Edinburgh BBSRC Discovery Fellow2020 - 2023
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University of Manchester BBSRC Discovery Fellow2019 - 2020
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University of Manchester Postdoctoral Research Associate2015 - 2019
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University of Manchester PhD Student2012 - 2015
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London School of Hygiene & Tropical Medicine Part-time PhD Student and Research Assistant2010 - 2012
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Royal London Hospital Supernumerary Trainee Clinical Scientist2008 - 2009
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UCB Celltech Research Associate2006 - 2008
Education
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University of Manchester PhD in Immunology2010 - 2015
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King's College London Postgraduate Certificate, Medical Immunology2008 - 2009
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University of Cambridge BA (Hons) Natural Sciences, Pathology2003 - 2006
Projects & Funding
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Determining how the microbiota and dietary selenium influence the function of long-lived intestinal macrophages to promote gut health Biotechnology and Biological Sciences Research Council2018 - 2023
Publications (30)
- Type I IFN-induced IFN- instructs monocyte-mediated systemic bacterial protection during type 2 intestinal helminth infection Save
- CD163 and Tim-4 identify resident intestinal macrophages that are spatially regulated by TGF-β. Save
- Comprehensive analysis of myeloid reporter mice Save
- LSD1 drives intestinal epithelial maturation and controls small intestinal immune cell composition independent of microbiota in a murine model Save
- Kidney resident macrophages have distinct subsets and multifunctional roles Save
- A subset of CD4+ effector memory T cells limit immunity to pulmonary viral infection and prevent tissue pathology via activation of latent TGFβ Save
- Do Concentration or Activity of Selenoproteins Change in Acute Stroke Patients? A Systematic Review and Meta-Analyses Save
- Memory CD8+ T cells exhibit tissue imprinting and non-stable exposure-dependent reactivation characteristics following blood-stage Plasmodium berghei ANKA infections Save
- Ongoing Exposure to Peritoneal Dialysis Fluid Alters Resident Peritoneal Macrophage Phenotype and Activation Propensity Save
- Alterations in T and B cell function persist in convalescent COVID-19 patients Save
- Hematopoietic stem and progenitor cells are present in healthy gingiva tissue Save
- Longitudinal immune profiling reveals key myeloid signatures associated with COVID-19 Save
- Rate of replenishment and microenvironment contribute to the sexually dimorphic phenotype and function of peritoneal macrophages Save
- ILC2s mediate systemic innate protection by priming mucus production at distal mucosal sites Save
- Infection-Induced Resistance to Experimental Cerebral Malaria Is Dependent Upon Secreted Antibody-Mediated Inhibition of Pathogenic CD8+ T Cell Responses. Save
- Antibiotics induce sustained dysregulation of intestinal T cell immunity by perturbing macrophage homeostasis Save
- Tissue-resident macrophages in the intestine are long lived and defined by Tim-4 and CD4 expression Save
- Macrophages in gastrointestinal homeostasis and inflammation Save
- A quantitative brain map of experimental cerebral malaria pathology Save
- Long-Lived CD4+IFN-γ+ T Cells rather than Short-Lived CD4+IFN-γ+IL-10+ T Cells Initiate Rapid IL-10 Production To Suppress Anamnestic T Cell Responses during Secondary Malaria Infection Save