Noor Akbar
University of Derby, University of Sharjah, Sunway University, Pakistan Institute of Engineering and Applied Sciences, American University of Sharjah, University of Peshawar
Research areas: Immunology and Microbiology · Applied Microbiology and Biotechnology · Legionella and Acanthamoeba research · Antimicrobial agents and applications · Nanoparticle-Based Drug Delivery
0000-0002-8114-1969
About
I am a molecular microbiologist and infectious disease researcher with over six years of postdoctoral experience in molecular microbiology, bacteriology, antimicrobial resistance, bacterial pathogenesis, host–pathogen interactions and infection biology. My research integrates bacterial molecular genetics, functional genomics, transcriptomics, metabolomics and in vitro cellular models to investigate microbial virulence, host responses, antimicrobial resistance and novel antimicrobial strategies. I have extensive expertise in bacterial culture and characterisation, PCR/RT-PCR, DNA/RNA manipulation, cloning, recombinant DNA technology and molecular analysis of pathogens, alongside cell culture and cellular assays using normal and cancer cell lines, human cerebral microvascular endothelial cells and mesenchymal stromal cells. My research includes pathogenic free-living amoebae, including Naegleria fowleri, Acanthamoeba castellanii and Balamuthia mandrillaris, and the investigation of gut bacterial metabolites and their effects on human cells using metabolomics and host-cell transcriptomics. I have authored several peer-reviewed publications, contributing to research in infectious diseases, AMR, microbial pathogenesis, emerging pathogens and host–microbe interactions.
Employment
-
University of Derby Research Fellow (Visiting)2024 - Present
-
University of Sharjah Postdoctoral Research Associate2022 - 2024
-
American University of Sharjah Postdoctoral Researcher2020 - 2022
-
National Institute for Biotechnology and Genetic Engineering Senior Research Fellow2019 - 2020
Education
-
Sunway University PhD in Biology (Molecular Microbiology)2016 - 2020
-
Pakistan Institute of Engineering and Applied Sciences M. Phil. Biotechnology (Molecular Biology)2013 - 2015
-
University of Peshawar BS (Hons) Microbiology2009 - 2013
Projects & Funding
Projects & funding information is unavailable.
Publications (59)
- Glucosamine functionalized multi-walled carbon nanotubes as potential antibacterial molecules Save
- Exploring the gut microbiome of Mugil cephalus for antibacterial agents using liquid chromatography Save
- Biocompatibility and drug release kinetics of TiNbZrSn femtosecond laser-induced superhydrophilic structures Save
- Phosphonium chloride--based deep eutectic solvents inhibit pathogenic Acanthamoeba castellanii belonging to the T4 genotype Save
- Antibacterial effects of quercetagetin are significantly enhanced upon conjugation with chitosan engineered copper oxide nanoparticles Save
- Azole-based compounds as potential anti-Acanthamoeba agents Save
- Nanomedicine: Patuletin-conjugated with zinc oxide exhibit potent effects against Gram-negative and Gram-positive bacterial pathogens Save
- Next generation imidazothiazole and imidazooxazole derivatives as potential drugs against brain-eating amoebae Save
- One pot synthesis of 5-hydroxyalkylated thiadiazine thiones: Implication in pain management and bactericidal properties Save
- Potential anti-amoebic activity of sulfonate-and sulfamate-containing carboxamide derivatives against pathogenic Acanthamoeba castellanii belonging to the genotype T4 Save
- Anti-amoebic activity of a series of benzofuran/benzothiophene derivatives against Acanthamoeba castellanii belonging to the T4 genotype Save
- Antiamoebic properties of Methyltrioctylammonium chloride based deep eutectic solvents Save
- Antibacterial properties of ethacridine lactate and sulfmethoxazole loaded functionalized graphene oxide nanocomposites Save
- Antimicrobial activity of novel deep eutectic solvents Save
- Azole and 5-nitroimidazole based nanoformulations are potential antiamoebic drug candidates against brain-eating amoebae Save
- Cinnamic acid and lactobionic acid based nanoformulations as a potential antiamoebic therapeutics Save
- Gut microbiome of Crocodylus porosus and cellular stress: inhibition of nitric oxide, interleukin 1-beta, tumor necrosis factor-alpha, and prostaglandin E2 in cerebrovascular endothelial cells Save
- Mass spectrometric analysis of bioactive conditioned media of bacteria isolated from reptilian gut Save
- Selected gut bacteria from water monitor lizard exhibit effects against pathogenic Acanthamoeba castellanii belonging to the T4 genotype Save
- The anti-amoebic potential of carboxamide derivatives containing sulfonyl or sulfamoyl moieties against brain-eating Naegleria fowleri Save