Adarsh Kumar

Employment

• Goethe University Frankfurt Postdoctoral scholar
  2022 - Present
• Florida State University Postdoctoral researcher
  2018 - 2021

Education

• Institute of Microbial Technology PhD
  2012 - 2018

Projects & Funding

Projects & funding information is unavailable.

Publications (16)

• Selective Macrocyclic WEE1 Kinase Inhibitors with Strong Efficacy against Patient-Derived Colorectal Cancer Organoids
  Journal of Medicinal Chemistry 2026 DOI: 10.1021/acs.jmedchem.6c00018
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• Discovery of APO-50815, a potent WEE1 kinase inhibitor with exceptional efficacy against patient-derived colorectal cancer organoids
  European Journal of Medicinal Chemistry 2026 DOI: 10.1016/j.ejmech.2026.118838
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• Structure-Based Design of PROTACS for the Degradation of Soluble Epoxide Hydrolase
  Journal of Medicinal Chemistry 2025 DOI: 10.1021/acs.jmedchem.5c00552
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• Critical assessment of LC3/GABARAP ligands used for degrader development and ligandability of LC3/GABARAP binding pockets
  Nature Communications 2024 DOI: 10.1038/s41467-024-54409-5
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• Discovery of the sEH Inhibitor Epoxykynin as a Potent Kynurenine Pathway Modulator
  Journal of Medicinal Chemistry 2024 DOI: 10.1021/acs.jmedchem.3c02245
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• Photosensitization enables Pauson-Khand–type reactions with nitrenes
  Science 2024 DOI: 10.1126/science.adm8095
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• STRUCTURE-BASED DESIGN OF PROTACS FOR THE DEGRADATION OF SOLUBLE EPOXIDE HYDROLASE
  Biorxiv 2024 DOI: 10.1101/2024.09.05.611393
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• Stoichiometry of ligand binding and role of C-terminal lysines in Mycobacterium tuberculosis and human GAPDH multifunctionality
  FEBS Journal 2024 DOI: 10.1111/febs.17298
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• The catalytic domain of free or ligand bound histone deacetylase 4 occurs in solution predominantly in closed conformation
  Protein Science 2024 DOI: 10.1002/pro.4917
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• Targeting LC3/GABARAP for degrader development and autophagy modulation
  2023 DOI: 10.1101/2023.10.05.560930
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