Tomoyuki Koga

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Publications (73)

• Integration of Computational Pipeline to Streamline Efficacious Drug Nomination and Biomarker Discovery in Glioblastoma
  Danielle Maeser, Robert F. Gruener, Robert Thomas Galvin +7 more
  Cancers 2024 DOI: 10.3390/cancers16091723
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• Stem cell modeling of nervous system tumors
  Disease Models & Mechanisms 2024 DOI: 10.1242/dmm.050533
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• Age-Dependent Hemorrhage Risk and Obliteration Benefit After Radiosurgery for Brain Arteriovenous Malformation
  International Journal of Radiation Oncology Biology Physics 2023 DOI: 10.1016/j.ijrobp.2023.02.059
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• Integrated analysis of single-cell chromatin state and transcriptome identified common vulnerability despite glioblastoma heterogeneity
  Proceedings of the National Academy of Sciences 2023 DOI: 10.1073/pnas.2210991120
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• Randomized phase III study of high-dose methotrexate and whole-brain radiotherapy with/without temozolomide for newly diagnosed primary CNS lymphoma
  Neuro-Oncology 2023 DOI: 10.1093/neuonc/noac246
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• Cooperativity between H3.3K27M and PDGFRA poses multiple therapeutic vulnerabilities in human iPSC-derived diffuse midline glioma avatars
  Kasey Skinner, Tomoyuki Koga, Shunichiro Miki +17 more
  2023 DOI: 10.1101/2023.02.24.528982
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• Pioneering models of pediatric brain tumors
  Neoplasia 2023 DOI: 10.1016/j.neo.2022.100859
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• TERT promoter C228T mutation in neural progenitors confers growth advantage following telomere shortening in vivo
  Neuro-Oncology 2022 DOI: 10.1093/neuonc/noac080
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• Structural studies of SALL family protein zinc finger cluster domains in complex with DNA reveal preferential binding to an AATA tetranucleotide motif
  Journal of Biological Chemistry 2022 DOI: 10.1016/j.jbc.2022.102607
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• Erratum
  Neuro-Oncology 2022 DOI: 10.1093/neuonc/noac178
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• Developing Bottom-Up Induced Pluripotent Stem Cell Derived Solid Tumor Models Using Precision Genome Editing Technologies
  The CRISPR Journal 2022 DOI: 10.1089/crispr.2022.0032
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• High Dose Radiosurgery Targeting the Primary Tumor Sites Contributes to Survival in Patients With Skull Base Chordoma.
  International journal of radiation oncology, biology, physics 2022 DOI: 10.1016/j.ijrobp.2022.02.024
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• Structural Insights into At-Rich DNA Recognition by Sall Family Proteins
  2022 DOI: 10.2139/ssrn.4162701
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• Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug
  Cell reports 2021 DOI: 10.1016/j.celrep.2021.109957
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• PTEN deficiency leads to proteasome addiction
  Neuro-Oncology 2021 DOI: 10.1093/neuonc/noab001
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• PI3Kγ inhibition suppresses microglia/TAM accumulation in glioblastoma microenvironment to promote exceptional temozolomide response
  Proceedings of the National Academy of Sciences 2021 DOI: 10.1073/pnas.2009290118
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• PI3K-GAMMA INHIBITION SUPPRESSES ACCUMULATION OF GLIOBLASTOMA-ASSOCIATED MICROGLIA TO RECAPITULATE THE MICROENVIRONMENT OF EXCEPTIONAL RESPONDERS
  Neuro-Oncology 2020
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• SMARCB1 loss interacts with neuronal differentiation state to block maturation and impact cell stability.
  Genes & development 2020 DOI: 10.1101/gad.339978.120
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• Epidermal Growth Factor Receptor (EGFR) as a molecular determinant of glioblastoma response to dopamine receptor 2 (DRD2) inhibitors.
  Neuro-oncology 2020 DOI: 10.1093/neuonc/noaa188
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• Epidermal Growth Factor Receptor (EGFR) as a molecular determinant of glioblastoma response to dopamine receptor 2 (DRD2) inhibitors.
  Neuro-Oncology 2020
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