Dr. Nikolay T. Tzvetkov
Also known as: Assoc. Prof. Dr. Nikolay T. Tzvetkov
Schwarz Pharma AG, Bulgarian Academy of Sciences, UCB SA
Research areas: Social Sciences · Health · Social Media in Health Education · scientometrics and bibliometrics research · Phytochemicals and Antioxidant Activities
0000-0002-8482-0481
About
Drug discovery research leader (Principle Investigator, Group Leader and Department Head) with extensive experience in synthetic organic chemistry, photochemistry, medicinal chemistry, macromolecular chemistry, combinatorial chemistry, and lead generation and optimization. Significant research achievements towards identification of new, single- and multitarget-directed drugs for the treatment of diseases of the central nervous system (CNS). Research interests: Drug Design & Development, Natural Products, Neurobiology, Molecular Pharmacology, Cheminformatics. Key accomplishments:
- Discovered reversible monoamine oxidase B (MAO-B) and dual MAO-A/B inhibitors.
- Developed a novel X-ray technology platform.
- Phenylethynylxanthine derivatives as A2a agonists /MAO-B inhibitors.
Employment
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Schwarz Pharma AG Postdoctoral Research Fellow
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Bulgarian Academy of Sciences Associate Professor and Head of Department
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UCB SA
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NTZ Lab Ltd. Founder/Project Manager Global
Education
Education history is unavailable.
Projects & Funding
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Multitarget peptide-fragment hybrids for the treatment of neurodegenerative diseases Bulgarian National Science Fund (BNSF)2019 - 2021
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Reductive photo-induced electron transfer reactions for synthesis of quasi-natural products Innovation Funds of the University of Bielefeld2001 - 2002
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Reductive and oxidative photo-induced electron transfer processes Volkswagen Foundation (VolkswagenStiftung)2000 - 2001
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Dynamic behavior of heterogeneous catalytic reactions German Academic Exchange Service (DAAD)1998 - 1998
Publications (32)
- Current research in biotechnology: Exploring the biotech forefront Save
- Carboxamides vs. methanimines: Crystal structures, binding interactions, photophysical studies, and biological evaluation of (indazole-5-yl)methanimines as monoamine oxidase B and acetylcholinesterase inhibitors Save
- Targeting Foam Cell Formation in Atherosclerosis: Therapeutic Potential of Natural Products Save
- Molecular neuroscience at its 'high': bibliometric analysis of the most cited papers on endocannabinoid system, cannabis and cannabinoids Save
- Monoamine Oxidases (MAOs) as Privileged Molecular Targets in Neuroscience: Research Literature Analysis Save
- Food toxicology: quantitative analysis of the research field literature Save
- Curcumin: Total-Scale Analysis of the Scientific Literature Save
- The berries on the top Save
- (Pyrrolo-pyridin-5-yl)benzamides: BBB permeable monoamine oxidase B inhibitors with neuroprotective effect on cortical neurons Save
- Antioxidants: Scientific Literature Landscape Analysis Save
- Phytochemicals as potent modulators of autophagy for cancer therapy Save
- Vascular smooth muscle cell proliferation as a therapeutic target. Part 1: molecular targets and pathways Save
- Vascular smooth muscle cell proliferation as a therapeutic target. Part 2: Natural products inhibiting proliferation Save
- Ethnopharmacological Approaches for Dementia Therapy and Significance of Natural Products and Herbal Drugs Save
- Autophagy and Alzheimer’s Disease: From Molecular Mechanisms to Therapeutic Implications Save
- Natural product-based multitargeted ligands for Alzheimer’s disease treatment? Save
- Vasculoprotective Effects of Pomegranate (Punica granatum L.) Save
- When neuroscience meets pharmacology: A neuropharmacology literature analysis Save
- Tautomerism of N-(3,4-dichlorophenyl)-1H-indazole-5-carboxamide – A new selective, highly potent and reversible MAO-B inhibitor Save
- Subnanomolar indazole-5-carboxamide inhibitors of monoamine oxidase B (MAO-B) continued: indications of iron binding, experimental evidence for optimised solubility and brain penetration Save