Ashok Sekhar

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Publications (44)

• Functional regulation of an intrinsically disordered protein via a conformationally excited state.
  Science advances 2023 DOI: 10.1126/sciadv.adh4591
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• Studying micro to millisecond protein dynamics using simple amide 15N CEST experiments supplemented with major-state R2 and visible peak-position constraints.
  Journal of biomolecular NMR 2023 DOI: 10.1007/s10858-023-00419-2
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• Probing excited state 1Hα chemical shifts in intrinsically disordered proteins with a triple resonance-based CEST experiment: Application to a disorder-to-order switch.
  Methods (San Diego, Calif.) 2023 DOI: 10.1016/j.ymeth.2023.08.009
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• Characterizing Post-Translational Modifications and Their Effects on Protein Conformation Using NMR Spectroscopy.
  Biochemistry 2019 DOI: 10.1021/acs.biochem.9b00827
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• Engineering Order and Cooperativity in a Disordered Protein.
  Biochemistry 2019 DOI: 10.1021/acs.biochem.9b00182
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• An NMR View of Protein Dynamics in Health and Disease.
  Annual review of biophysics 2019 DOI: 10.1146/annurev-biophys-052118-115647
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• Measuring Diffusion Constants of Invisible Protein Conformers by Triple-Quantum 1 H CPMG Relaxation Dispersion.
  Angewandte Chemie (International ed. in English) 2018 DOI: 10.1002/anie.201810868
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• Conserved conformational selection mechanism of Hsp70 chaperone-substrate interactions.
  eLife 2018 DOI: 10.7554/eLife.32764
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• Effects of maturation on the conformational free-energy landscape of SOD1.
  Proceedings of the National Academy of Sciences of the United States of America 2018 DOI: 10.1073/pnas.1721022115
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• An enhanced sensitivity methyl 1H triple-quantum pulse scheme for measuring diffusion constants of macromolecules.
  Journal of biomolecular NMR 2017 DOI: 10.1007/s10858-017-0122-9
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