Ranit Dutta
Brigham and Women's Hospital, University of Massachusetts, Indian Institute of Technology Kanpur, University of Kalyani
About
I am a postdoctoral fellow in the Joshi Lab at Harvard Medical School, where I aim to develop prophylactic nasal sprays for allergens and utilize biomolecular condensates for therapy. I completed my doctoral studies in the Thayumanavan Lab within the Department of Chemistry at the University of Massachusetts Amherst. My doctoral research centered on designing activatable targeted protein degraders, achieving precise tissue delivery through active targeting, and utilizing antibody-polymer conjugates for the lysosomal degradation of membrane proteins.
Employment
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Brigham and Women's Hospital Postdoctoral Fellow2025 - 2027
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University of Massachusetts PhD2019 - 2025
Education
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Indian Institute of Technology Kanpur Master of Science2017 - 2019
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University of Kalyani Bachelor of Science2014 - 2017
Projects & Funding
Projects & funding information is unavailable.
Publications (11)
- Enzyme Activation of Triggerable Polymeric Lysosome Targeting Chimeras Save
- Expanding the Repertoire of Lysosomal Degradation of Membrane Proteins: A Generalizable Strategy Using Multivalent Antibody−Polymer Chimeras Save
- Systematic Engineering of Intra-Articular Drug Release Profiles Reveals a Key Determinant of Disease-Modifying Efficacy in Post-Traumatic Osteoarthritis Save
- Multicheckpoint Cellular Targeting of siRNAs Using Antibody-Directed Lipid-Polymer Hybrid Nanoparticles Save
- Dual-Action-Only PROTACs Save
- Multivalent Ligand-Protein Interactions Using Polymeric Lysosome-Targeting Chimeras (PolyTACs) Leads to Lysosome-Targeting Receptor-Independent Degradation of Transmembrane Proteins Save
- Polymers for Disrupting Protein–Protein Interactions: Where Are We and Where Should We Be? Save
- Intramolecular Electrostatic Interactions Regulate Reactivity of Zwitterionic Functionalities in Amphiphilic Assemblies Save
- Conferring liver selectivity to a thyromimetic using a novel nanoparticle increases therapeutic efficacy in a diet-induced obesity animal model Save
- Multisite Labeling of Proteins Using the Ligand-Directed Reactivity of Triggerable Michael Acceptors Save