Hongchao Guo

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Publications (18)

• Epigenetic regulation of cardiovascular diseases induced by behavioral and environmental risk factors: Mechanistic, diagnostic, and therapeutic insights
  FASEB BioAdvances 2024 DOI: 10.1096/fba.2024-00080
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• SGLT2 inhibitor ameliorates endothelial dysfunction associated with the common ALDH2 alcohol flushing variant
  Hongchao Guo, Xuan Yu, Yu Liu +19 more
  Science Translational Medicine 2023 DOI: 10.1126/scitranslmed.abp9952
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• Systems analysis of de novo mutations in congenital heart diseases identified a protein network in the hypoplastic left heart syndrome.
  Cell systems 2022 DOI: 10.1016/j.cels.2022.09.001
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• Deciphering pathogenicity of variants of uncertain significance with CRISPR-edited iPSCs.
  Trends in genetics : TIG 2021 DOI: 10.1016/j.tig.2021.08.009
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• Endogenous Retrovirus-Derived lncRNA BANCR Promotes Cardiomyocyte Migration in Humans and Non-human Primates.
  Developmental cell 2020 DOI: 10.1016/j.devcel.2020.07.006
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• Maternal Smoking Induced Cardiovascular Risks in Fetuses: How Can in silico Models Help?
  Frontiers in bioengineering and biotechnology 2020 DOI: 10.3389/fbioe.2020.00097
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• RRAD mutation causes electrical and cytoskeletal defects in cardiomyocytes derived from a familial case of Brugada syndrome.
  Nadjet Belbachir, Vincent Portero, Zeina Reda Al Sayed +30 more
  European heart journal 2019 DOI: 10.1093/eurheartj/ehz308
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• Modeling Cardiovascular Risks of E-Cigarettes With Human-Induced Pluripotent Stem Cell-Derived Endothelial Cells.
  Won Hee Lee, Sang‐Ging Ong, Yang Zhou

  +11 more

  • Lei Tian
  • Hye Ryeong Bae
  • Natalie Baker
  • Adam Whitlatch
  • Leila Mohammadi
  • +6 more
  Journal of the American College of Cardiology 2019 DOI: 10.1016/j.jacc.2019.03.476
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• A Human iPSC Double-Reporter System Enables Purification of Cardiac Lineage Subpopulations with Distinct Function and Drug Response Profiles.
  Cell stem cell 2019 DOI: 10.1016/j.stem.2019.02.015
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• Single-Cell RNA Sequencing of Human Embryonic Stem Cell Differentiation Delineates Adverse Effects of Nicotine on Embryonic Development.
  Stem cell reports 2019 DOI: 10.1016/j.stemcr.2019.01.022
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• Induced pluripotent stem cells as a biopharmaceutical factory for extracellular vesicles.
  European heart journal 2018 DOI: 10.1093/eurheartj/ehy097
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• Applications of genetically engineered human pluripotent stem cell reporters in cardiac stem cell biology.
  Current opinion in biotechnology 2018 DOI: 10.1016/j.copbio.2018.03.002
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• SETD7 Drives Cardiac Lineage Commitment through Stage-Specific Transcriptional Activation.
  Cell stem cell 2018 DOI: 10.1016/j.stem.2018.02.005
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• RNAi Reveals Phase-Specific Global Regulators of Human Somatic Cell Reprogramming.
  Cheng-Xu Delon Toh, J. C. W. Chan, Zheng‐Shan Chong

  +17 more

  • Haofei Wang
  • Hongchao Guo
  • Sandeep Satapathy
  • Dongrui Ma
  • Germaine Yen Lin Goh
  • +12 more
  Cell reports 2016 DOI: 10.1016/j.celrep.2016.05.049
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• Cops2 promotes pluripotency maintenance by Stabilizing Nanog Protein and Repressing Transcription.
  Scientific reports 2016 DOI: 10.1038/srep26804
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• Erk signaling is indispensable for genomic stability and self-renewal of mouse embryonic stem cells.
  Proceedings of the National Academy of Sciences of the United States of America 2015 DOI: 10.1073/pnas.1516319112
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• Systematic identification of factors for provirus silencing in embryonic stem cells.
  Cell 2015 DOI: 10.1016/j.cell.2015.08.037
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• Role of nuclear receptor coactivator 3 (Ncoa3) in pluripotency maintenance.
  The Journal of biological chemistry 2012 DOI: 10.1074/jbc.m112.373092
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