JX

Jian ping Xie

Southwest University

Research areas: Medicine · Infectious Diseases · Tuberculosis Research and Epidemiology · Bacterial Genetics and Biotechnology · Mycobacterium research and diagnosis

ORCID iD 0000-0002-8959-8146
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About

Jian Ping Xie, Ph.D. Professor, Deputy director
[email protected]
[email protected]
Affiliations
Institute of Modern Biopharmaceuticals,
School of Life Sciences,Southwest University,
Beibei, Chongqing,China,400715
Tel&Fax:86-23-68367108
Research interests
Our laboratory has broad interest in the application of cutting edge ideas and technology to the study of key or emerging pathogen-relevant issues, especially the Mycobacterium tuberculosis. Major directions include pathogen and related mycobacteriophages -centered microbiology, molecular immunology, genetics, epigenetics, drug/drug target discovery/screen, signal transduction, functional genomics and proteomics, gene regulation, T cell receptor repertoire. Clinical issues of interest include tuberculosis-oriented infection and inflammation. We currently rely heavily on single cell genomics, RNA-Seq and Itraq analysis, RNA interference in cell line and model animals such as zebrafish, clinical patient samples, integrated with canonical means involved in the study of global regulation of transcriptional factors, signal transduction, transcription, protein-interaction and modification, coupled with biological queries to understand the pathogenesis of pathogen and host difference of innate and adaptive immunity between health and diseases. Trainees routinely are exposed to a variety of expertises and methodologies, and will usually be highly competitive after this training.
Specifically, we focused on three organisms:
1. Mycobacterium tuberculosis,its molecular physiology, genetics and transcriptional regulation, post-translational modification,epigenetics,networks involvd in persistence and drug resistance.
2. Mycobacteriophages, novel phages isolation, sequencing and functional definition, interaction network with its host Mycobacterium as preclude for better antibiotics discovery.
3. Host, largely active or latent tuberculosis patients, and HIV coinfection individuals, together with cell lines to pinpoint underlying pathogenesis key culprit, for better intervention measures.
4. Big data and bioinformatics for biomarkers of tuberculosis diagnosis, treatment efficacy monitoring.

A list of publications can be retrieved from PubMed using the author name(XIE JP) and affiliation(SOUTHWEST UNIVERSITY).
Education and Research experiences
1989-1993, Southwest normal university, biology, Bachelor
1996-2002, Fudan University, microbiology, master and PhD
1993-present, School of Life Sciences, Southwest University (before 2005 named Southwest normal university)
2009-2010, Global Tuberculosis Center, Public health research institute, University of Medical and Dentistry of New Jersey( Rutgers-New Jersey Medical School) visiting scholar sponsored by China Schorlarship Council
2011, Bloomberg School of Public Health, Johns Hopkins University,sensior research schorlar sponsored by China Schorlarship Council
2012, Weill Medical College, Cornell University, sensior research schorlar sponsored by China Schorlarship Council
2015,Perelman School of Medicine, University of Pennsylvania, sensior research schorlar sponsored by China Schorlarship Council
2016, Global Tuberculosis Center, Public health research institute, University of Medical and Dentistry of New Jersey( Rutgers-New Jersey Medical School) visiting scholar sponsored by China Schorlarship Council
2017,Global Tuberculosis Center, Public health research institute, Rutgers University visiting scholar sponsored by China Schorlarship Council
2018,Global Tuberculosis Center, Public health research institute, Rutgers University visiting scholar sponsored by China Schorlarship Council
Honors
Special stipend award by the central government, 2010
New century excellent talents in Universities, 2011
Outstanding Mentor Award of PhD supervisor,2011
Distintuished teaching and reform award by Southwest University 2008,2010,2012
Service
Deputy director of Chongqing society of microbiology,
Associated editor-in-Chief of HEREDITAS(BEIJING)YI CHUAN
Acta Microbiologia Sinica, Editorial Board, 2011-2016
Acta Pharmaceutica Sinica, Editorial Board, 2013-
Committee member of multiple societies, such as genetics,immunology,pharmacology, bioengineering， industry promotion.
miscellaneous NSFC reviewer,2003-;

Ad hoc reviewer: genetics, general microbiology, bioengineering, cell biology, bioluminescence, current microbiology,BMC series, Nature protocol. South Africa Medical research Council, Korea science foundation, Portland science foundation.

Employment

Education

Education history is unavailable.

Projects & Funding

Projects & funding information is unavailable.

Publications (3)