About
•Rational design and synthesis of small molecule libraries for target identification, hit-to-lead, lead optimization, and SAR studies. ADME optimization.
• Anti-cancer Agents: Kinase inhibitors- IGF1R, EGFR and EZH2 inhibitors
• Infectious Diseases drug discovery: Tuberculosis (TB), Malaria.
• Neglected Tropical Diseases: Human African Trypanosomiasis, Chagas Disease
• Antibacterial, Antifungal, Antibiotic, and anti-inflammatory agents.
•Drug repurposing of human kinase inhibitors for the treatment of Neglected Tropical Diseases.
•Design and synthesis of azaspirocyles and their applications in medicinal chemistry.
•Synthetic organic chemistry- Heterocyclic chemistry, Fluorine chemistry.
•Protection and deprotection of hydroxyl group, nucleosides, and amino acids.
•Boisosteres- Applications in medicinal chemistry.
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