SA
Sara Abdelfatah
Johannes Gutenberg University Mainz, Institute of Endemic Diseases, University of Khartoum
Research areas: Pharmacology, Toxicology and Pharmaceutics · Drug Discovery · Computational Drug Discovery Methods · SARS-CoV-2 and COVID-19 Research · Drug Transport and Resistance Mechanisms
Employment
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Johannes Gutenberg Universität Mainz Postdoctoral researcher2019 - 2022
Education
- 2015 - 2019
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Institute of Endemic Diseases Master2012 - 2014
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University of Khartoum Bachelor2004 - 2009
Projects & Funding
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DAAD Research Grants - Doctoral Programmes in Germany. German Academic Exchange Service2015 - 2019
Publications (25)
- Identification of Antagonistic Action of Pyrrolizidine Alkaloids in Muscarinic Acetylcholine Receptor M1 by Computational Target Prediction Analysis Save
- Coronavirus Inhibitors Targeting nsp16 Save
- Network Pharmacology of Ginseng (Part III): Antitumor Potential of a Fixed Combination of Red Ginseng and Red Sage as Determined by Transcriptomics Save
- Potential Coronaviral Inhibitors of the Nucleocapsid Protein Identified In Silico and In Vitro from a Large Natural Product Library Save
- Correction to: Identification and characterization of deschloro-chlorothricin obtained from a large natural product library targeting aurora A kinase in multiple myeloma Save
- In Silico and In Vitro Identification of Pan-Coronaviral Main Protease Inhibitors from a Large Natural Product Library Save
- Network Pharmacology of Red Ginseng (Part I): Effects of Ginsenoside Rg5 at Physiological and Sub-Physiological Concentrations Save
- Network Pharmacology of Red Ginseng (Part I): Effects of Ginsenoside Rg5 at Physiological and Sub-Physiological Concentrations Save
- Network Pharmacology of Ginseng (Part II): The Differential Effects of Red Ginseng and Ginsenoside Rg5 in Cancer and Heart Diseases as Determined by Transcriptomics Save
- Network Pharmacology of Ginseng (Part II): The Differential Effects of Red Ginseng and Ginsenoside Rg5 in Cancer and Heart Diseases as Determined by Transcriptomics Save
- Isopetasin and S-isopetasin as novel P-glycoprotein inhibitors against multidrug-resistant cancer cells Save
- Identification and characterization of deschloro-chlorothricin obtained from a large natural product library targeting aurora A kinase in multiple myeloma Save
- Cytotoxicity of apigenin toward multiple myeloma cell lines and suppression of iNOS and COX-2 expression in STAT1-transfected HEK293 cells Save
- N-acetylglycoside of oleanolic acid (aridanin) displays promising cytotoxicity towards human and animal cancer cells, inducing apoptotic, ferroptotic and necroptotic cell death Save
- 8,8-bis-(Dihydroconiferyl)-diferulate displayed impressive cytotoxicity towards a panel of human and animal cancer cells Save
- The antioxidant 2,3-dichloro,5,8-dihydroxy,1,4-naphthoquinone inhibits acetyl-cholinesterase activity and amyloid β42 aggregation: A dual target therapeutic candidate compound for the treatment of Alzheimer's disease. Save
- Cytotoxicity and antimitotic activity of Rhinella schneideri and Rhinella marina venoms. Save
- Cytotoxicity of 40 Egyptian plant extracts targeting mechanisms of drug-resistant cancer cells Save
- Identification of inhibitors of the polo-box domain of polo-like kinase 1 from natural and semisynthetic compounds. Save
- A selective inhibitor of the Polo-box domain of Polo-like kinase 1 identified by virtual screening Save