LG
Lindsey Goodman
University of Pennsylvania, The University of Texas MD Anderson Cancer Center, The University of Texas at Austin
Research areas: Medicine · Oncology · Glioma Diagnosis and Treatment · Alzheimer's disease research and treatments · Cancer Cells and Metastasis
0000-0002-9255-3811
Employment
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University of Pennsylvania Teaching Assistant2014 - 2014
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The University of Texas MD Anderson Cancer Center Senior Research Assistant2007 - 2012
Education
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University of Pennsylvania Doctor of Philosophy2012 - 2019
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University of Texas at Austin Bachelors of Science2002 - 2007
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University of Texas at Austin Bachelors of Science2002 - 2006
Projects & Funding
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The characterization of mutations in TNPO2 that are associated with a rare developmental disease. TNPO2 Foundation2022 - 2025
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Defining connections between ROS-induced glial lipid droplets and Tau in Alzheimer's Disease BrightFocus Foundation2021 - 2024
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Multidisciplinary Training in Brain Disorders and Development National Institute of Neurological Disorders and Stroke2020 - 2021
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Graduate training in systems and integrative biology National Institute of General Medical Sciences2012 - 2014
Publications (19)
- The spatiotemporal evolution of radiation resistance in glioblastoma Save
- Revealing the nervous system requirements of Alzheimer’s disease risk genes in Drosophila Save
- Does glial lipid dysregulation alter sleep in Alzheimer's and Parkinson's disease? Save
- Glial lipid droplets resolve ROS during sleep. Save
- Whole organism snRNA-seq reveals systemic peripheral changes in Alzheimer’s Disease fly models Save
- Autolysosomal exocytosis of lipids protect neurons from ferroptosis Save
- Neuronal ROS-Induced Glial Lipid Droplet Formation is Altered by Loss of Alzheimer’s Disease-associated Genes Save
- New Roles for Canonical Transcription Factors in Repeat Expansion Diseases. Save
- Repeat-associated non-AUG (RAN) translation mechanisms are running into focus for GGGGCC-repeat associated ALS/FTD. Save
- Toxic expanded GGGGCC repeat transcription is mediated by the PAF1 complex in C9orf72-associated FTD. Save
- Drosophila Ref1/ALYREF regulates transcription and toxicity associated with ALS/FTD disease etiologies. Save
- eIF4B and eIF4H mediate GR production from expanded G4C2 in a Drosophila model for C9orf72-associated ALS. Save
- ABT-888 restores sensitivity in temozolomide resistant glioma cells and xenografts. Save
- Dipeptide repeat proteins activate a heat shock response found in C9ORF72-ALS/FTLD patients. Save
- A gene expression signature predicts recurrence-free survival in meningioma. Save
- Percentage of mesenchymal stem cells in high-grade glioma tumor samples correlates with patient survival. Save
- Spt4 selectively regulates the expression of C9orf72 sense and antisense mutant transcripts. Save
- A fly model for the CCUG-repeat expansion of myotonic dystrophy type 2 reveals a novel interaction with MBNL1. Save
- Mesenchymal differentiation mediated by NF-κB promotes radiation resistance in glioblastoma. Save