Ryan T Muir
Sunnybrook Research Institute, University of Toronto, University of Calgary, Sunnybrook Health Science Centre, McMaster University
0000-0002-9349-1069
About
Over the next 30 years it is estimated that, cumulatively, more than 6 million Canadians will be diagnosed with dementia. In order to address this anticipated – and already rising – population health demand, we must identify novel approaches to facilitate early diagnosis, identify the most pertinent predictors of cognitive decline and use these as steppingstones to discover and deliver novel therapies. The cerebrovascular contributions to declining cognition and emergent dementia are undeniable. Dr Muir’s research foci center on cerebral small vessel disease, Cerebral Amyloid Angiopathy (CAA), hemorrhagic stroke, post stroke cognitive impairment, vascular dementia, Alzheimer’s Disease and amyloid immunotherapy risks. There are currently no treatments for CAA or cerebral small vessel disease, and the mainstay of therapy is vascular risk factor control. Dr. Muir’s research work has also evaluated novel and emerging blood-based biomarkers in CAA which may help advance diagnostic detection.
Employment
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Sunnybrook Research Institute Associate Scientist2025 - Present
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University of Toronto Assistant Professor2024 - Present
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Sunnybrook Health Science Centre Staff Neurologist2024 - Present
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University of Calgary Vascular Neurology Fellow2022 - 2024
Education
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University of Calgary Master's of Science - Clinical Epidemiology2022 - 2024
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University of Toronto Adult Neurology Residency Training Program2017 - 2022
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University of Toronto Medical Degree2013 - 2017
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McMaster University Bachelor of Health Sciences (Hons).2008 - 2012
Projects & Funding
Projects & funding information is unavailable.
Publications (49)
- Amyloid Related Imaging Abnormalities and ischemic stroke: a rapid review and meta-analysis of concurrent ischemic lesions and ARIA during anti-amyloid immunotherapy Save
- Automated perfusion imaging did not improve reliability of ASPECTS or collateral score in late-window large vessel occlusion stroke Save
- Associations Between Cerebral Amyloid Angiopathy, Cognitive Impairment, and Depressive Symptoms Save
- A Progressive Painful Bilateral Medial Medullary Stroke Syndrome Accompanied by an Evolving and Ominous Air-Pod Sign Save
- Association between cerebral small vessel disease and periodic limb movements of sleep in patients with stroke/TIA Save
- Plasma biomarkers distinguish Boston Criteria 2.0 cerebral amyloid angiopathy from healthy controls Save
- Clinical uncertainty in large vessel occlusion ischemic stroke: does automated perfusion imaging make a difference? An intra-rater and inter-rater agreement study Save
- Cognitive Assessments in Randomized Controlled Trials of Acute or Secondary Prevention Stroke Treatments 2011 to 2024: A Scoping Review Save
- Diagnosis and management of cerebral amyloid angiopathy: a scientific statement from the International CAA Association and the World Stroke Organization Save
- Minimal clinically important difference in Alzheimer's disease: Rapid review Save