Kumar Nikhil

About

Experienced molecular biologist with a demonstrated history of working in oncology and neurobiology. Strong research professional with a PhD in cancer biology from IIT Roorkee. Area of expertise involve Cancer biology, Neurodegenerative Diseases, Molecular Endocrinology, Cell Signalling, Tumor-stroma interaction.

Employment

• KIIT School of Biotechnology Assistant Professor
  2023 - Present
• Birla Institute of Technology and Science Pilani - K K Birla Goa Campus Assistant Professor
  2020 - Present
• Purdue University Postdoctoral Research Associate
  2015 - Present
• Indian Institute of Technology Roorkee Phd
  2009 - 2015

Education

Education history is unavailable.

Projects & Funding

Projects & funding information is unavailable.

Publications (48)

• CDK5: an oncogene or an anti-oncogene: location location location
  Molecular Cancer 2023 DOI: 10.1186/s12943-023-01895-8
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• LIMK2-NKX3.1 Engagement Promotes Castration-Resistant Prostate Cancer
  Cancers 2021 DOI: 10.3390/cancers13102324
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• Phosphorylation-dependent regulation of SPOP by LIMK2 promotes castration-resistant prostate cancer
  British Journal of Cancer 2021 DOI: 10.1038/s41416-020-01197-6
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• Molecular Interplay between AURKA and SPOP Dictates CRPC Pathogenesis via Androgen Receptor
  Cancers 2020 DOI: 10.3390/cancers12113247
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• Negative cross talk between LIMK2 and PTEN promotes castration resistant prostate cancer pathogenesis in cells and in vivo
  Cancer Letters 2020 DOI: 10.1016/j.canlet.2020.09.010
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• Aurora kinase a-ybx1 synergy fuels aggressive oncogenic phenotypes and chemoresistance in castration-resistant prostate cancer
  Cancers 2020 DOI: 10.3390/cancers12030660
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• A mitotic CDK5-PP4 phospho-signaling cascade primes 53BP1 for DNA repair in G1
  Nature Communications 2019 DOI: 10.1038/s41467-019-12084-x
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• Identification of LIMK2 as a therapeutic target in castration resistant prostate cancer
  Cancer Letters 2019 DOI: 10.1016/j.canlet.2019.01.035
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• Multifaceted Regulation of ALDH1A1 by Cdk5 in Alzheimer’s Disease Pathogenesis
  Molecular Neurobiology 2019 DOI: 10.1007/s12035-018-1114-9
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• Synthesis and anticancer activity studies of indolylisoxazoline analogues
  M.V.S.K. Chaitanya, P.O. Venkataramana Reddy, Kumar Nikhil +3 more
  Bioorganic and Medicinal Chemistry Letters 2018 DOI: 10.1016/j.bmcl.2018.07.035
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• Synthesis and investigations into the anticancer and antibacterial activity studies of β-carboline chalcones and their bromide salts
  Bioorganic and Medicinal Chemistry Letters 2018 DOI: 10.1016/j.bmcl.2018.03.033
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• Cdk5-Mcl-1 axis promotes mitochondrial dysfunction and neurodegeneration in Alzheimer's disease model
  Journal of Cell Science 2017 DOI: 10.1242/jcs.205666
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• Design, synthesis and in vitro cytotoxicity studies of novel β-carbolinium bromides
  Bioorganic and Medicinal Chemistry Letters 2017 DOI: 10.1016/j.bmcl.2017.02.010
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• Phosphorylation-dependent regulation of ALDH1A1 by Aurora kinase A: Insights on their synergistic relationship in pancreatic cancer
  BMC Biology 2017 DOI: 10.1186/s12915-016-0335-5
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• Synthesis, structural, solubility and anticancer activity studies of salts using nucleobases and sulfonic acids coformer
  Neetu Singh, Udai P. Singh, Kumar Nikhil +2 more
  Journal of Molecular Structure 2017 DOI: 10.1016/j.molstruc.2017.06.053
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• The Aurora-A-Twist1 axis promotes highly aggressive phenotypes in pancreatic carcinoma
  Journal of Cell Science 2017 DOI: 10.1242/jcs.196790
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• Design, synthesis, molecular docking, and biological studies of novel phytoestrogen-tanaproget hybrids
  Sumit Kumar, Nishant Verma, Kumar Nikhil +4 more
  Synthetic Communications 2016 DOI: 10.1080/00397911.2016.1144768
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• A novel gellan-PVA nanofibrous scaffold for skin tissue regeneration: Fabrication and characterization
  Priya Vashisth, Kumar Nikhil, Partha Roy +3 more
  Carbohydrate Polymers 2016 DOI: 10.1016/j.carbpol.2015.09.113
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• Drug functionalized microbial polysaccharide based nanofibers as transdermal substitute
  Priya Vashisth, Amit Srivastava, Hemant Kumar Nagar +7 more
  Nanomedicine: Nanotechnology, Biology, and Medicine 2016 DOI: 10.1016/j.nano.2016.01.019
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• Emergence of fluorescence in boron nitride nanoflakes and its application in bioimaging
  Vijayesh Kumar, Kumar Nikhil, Partha Roy +2 more
  RSC Advances 2016 DOI: 10.1039/c6ra05288f
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