Srinivas Murthy
University of British Columbia, BC Children's Hospital, McGill University, BC Children's Hospital Research Institute, Memorial University of Newfoundland
Research areas: Medicine · Infectious Diseases · COVID-19 Clinical Research Studies · Sepsis Diagnosis and Treatment · Respiratory Support and Mechanisms
About
Infections in children are still a major cause of early morbidity and mortality throughout the world, despite the advances made in preventive care. Infections are often a reason for children to become critically ill, and often occur in the critically ill child. My research focuses upon stemming this burden through optimizing their management in a variety of settings. Additionally, the ability of various settings and healthcare systems to cost-effectively manage critically ill children, especially those with infection, is an area of focus.
Employment
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University of British Columbia Associate Professor2017 - Present
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BC Children's Hospital Staff - Pediatric Critical Care2013 - Present
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BC Children's Hospital Research Institute Clinical Scientist2013 - Present
Education
- 2014 - 2016
- 2002 - 2006
- 1998 - 2002
Projects & Funding
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Host Response Mediators in Coronavirus (COVID-19) Infection Canadian Institutes of Health Research2020 - 2021
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Sex as a Biological Variable Supplement - Host Response Mediators in Coronavirus (COVID-19) Infection Canadian Institutes of Health Research2020 - 2021
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RIsk of environmental Surface and air Contamination in COVID19 (RISC-COV) Canadian Institutes of Health Research2020 - 2022
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COVID-19 Ring-based Prevention trial for Undermining Spread (CORPUS) Canadian Institutes of Health Research2020 - 2022
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Socio-Cultural Implications of COVID-19: Educating, Engaging & Empowering the Public Canadian Institutes of Health Research2020 - 2022
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Canadian Treatments for COVID-19: SOLIDARITY Canadian Institutes of Health Research2020 - 2020
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COVID-19: Improving the Evidence to Treat an Emerging Infection Through Observational Studies and a Randomized Trial Canadian Institutes of Health Research2020 - 2022
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Canadian Sepsis Research Network: Improving CareBefore, During and After Sepsis Canadian Institutes of Health Research2019 - 2020
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Canadian Sepsis Research Network: Improving Care Before, During and After Sepsis. Canadian Institutes of Health Research2019 - 2024
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AMRIC - Antimicrobial Resistance in Intensive Care Canadian Institutes of Health Research2019 - 2019
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Process Evaluation of the SuDDICU trial: An international randomized cluster crossover trial of the impact of a preventative antibiotic regimen (SDD) on patient outcome and antibiotic resistance within intensive care Canadian Institutes of Health Research2018 - 2021
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Rapid correction of vitamin D deficiency in pediatric critical illness: A phase III multicentre randomized controlled trial Canadian Institutes of Health Research2018 - 2023
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Canadian Adaptive Platform Trial in Intensive Care (CAPTIC) Program Canadian Institutes of Health Research2018 - 2022
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The SuDDICU study- A study of the impact of preventative antibiotics (SDD) on patient outcome and antibiotic resistance in the critically ill in intensive care Canadian Institutes of Health Research2017 - 2018
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The SuDDICU study- A study of the impact of preventative antibiotics (SDD) on patient outcome and antibiotic resistance in the critically ill in intensive care Canadian Institutes of Health Research2017 - 2020
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Gone, but not forgotten: A prospective cohort study to characterize the health effects of post-Ebola syndrome on survivors of Ebola Virus Disease in West Africa Canadian Institutes of Health Research2015 - 2016
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Establishing Feasibility & Safety of Providing Critical Care for Patients with Ebola through design of a simulated Ebola Treatment Centre Canadian Institutes of Health Research2015 - 2016
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Delivery of supportive care during an Ebola outbreak: defining minimal requirements and identifying barriers and facilitators towards creating international guidelines Canadian Institutes of Health Research2015 - 2016
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Clinical Presentation and Outcomes for Children with Enthesitis-Related Arthritis in the First 12 Months of Disease Canadian Institutes of Health Research2010 - 2011
Publications (353)
- Assessing the quality of consent discussions in intensive care unit research: A scoping review of outcome measures Save
- Considerations for environmental sustainability in clinical trials: A case study simulation of the REVISE trial Save
- Lessons learned and recommendations from the Canadian adaptive platform trial of treatments for COVID in community settings (CanTreatCOVID) Save
- Time to extracorporeal cardiopulmonary resuscitation flow and outcomes in paediatric in-hospital cardiac arrest: a 12-year single-centre study Save
- Which issues should be addressed in future trials regarding the use of corticosteroids in community acquired pneumonia? A survey of REMAP-CAP investigators Save
- Intermediate- versus prophylactic-dose heparin for hospitalised patients with COVID-19: an updated meta-analysis of randomised trials Save
- Socioeconomic Status, Rurality, and Pediatric Critical Care Admission Save
- Identifying Research Priorities in Canadian Adult and Pediatric Critical Care: Results From a James Lind Alliance Priority Setting Partnership Save
- Developing Canada's clinical research capacity and relevance: Change management issues Save
- Environmental Sustainability in Intensive Care: From Awareness to Action Save
- Core sociodemographic data variables reported in Canadian intensive care unit studies: a scoping review Save
- Éléments fondamentaux de la documentation du consentement à la recherche clinique au Canada : orientation stratégique Save
- Core elements of consent documentation for clinical research in Canada: guidance for policy Save
- CAEP 2024 Academic Symposium: adaptive platform trials in emergency medicine in Canada Save
- Evaluation of the Establishment of a Public and Patient Involvement and Engagement Group to Support Clinical Trials in Pakistan: Protocol for a Mixed-Methods Study Save
- Access to Limited Critical Care and Risk of Mortality in Rwanda: A Prospective Cohort Study Save
- Anticoagulation Among Patients Hospitalized for COVID-19 A Systematic Review and Prospective Meta-analysis Save
- Canadian Adaptive Platform Trial of Treatments for COVID in Community Settings (CanTreatCOVID): Protocol for a randomised controlled adaptive platform trial of treatments for acute SARS-CoV-2 infection in community settings Save
- Co-designing and pilot-testing an infographic to support the consent process in an adaptive platform trial for adults in ICU with community-acquired pneumonia or COVID-19: a mixed methods study within a trial (SWAT) Save
- Effect of hydrocortisone on mortality in patients with severe community-acquired pneumonia: The REMAP-CAP Corticosteroid Domain Randomized Clinical Trial Save