Mohammed Tanjimur Rahman
Also known as: Tanjim
Cleveland Clinic Lerner Research Institute, Shimane University, Dhaka Medical College and Hospital
0000-0002-9790-0069
About
As a physician scientist my goal is to seek answers to overcome major clinical challenges in the fields of cancer biology & cardiovascular pathology. My research activities include identification of novel therapeutic targets for ovarian, endometrial and triple negative breast cancer based on the large scale genomic data curation followed by confirmation through functional and biological assays. I am highly interested to study molecular pathways of cancer development to unveil how oncogenes helps to promote cancer transformations, molecular characteristics of metastatic cancers and development of chemotherapy resistance in cancer to expand my insight in to solid tumor pathology. I am also interested in macrophage polarization and its involvement in tissue inflammation i.e. atherosclerosis development and cancer metastasis. My current studies involve delivery of cancer chemotherapeutics, interfering RNA and epigenetics modulating drugs to secondary metastatic sites i.e. bone, brain and treating metastatic cancers more effectively and efficiently.
Employment
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Cleveland Clinic Lerner Research Institute Post-doctoral Research Fellow2019 - Present
Education
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Shimane University PhD2010 - 2014
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Dhaka Medical College and Hospital MBBS2000 - 2006
Projects & Funding
Projects & funding information is unavailable.
Publications (40)
- Efficacy and Safety of Dual Paclitaxel and Sirolimus Nanoparticle-Coated Balloon. Save
- Nanoparticle-mediated synergistic drug combination for treating bone metastasis. Save
- Effects of thrombospondin-4 on pro-inflammatory phenotype differentiation and apoptosis in macrophages Save
- Synergistic combination treatment to break cross talk between cancer cells and bone cells to inhibit progression of bone metastasis. Save
- Ectopic Otoconin 90 expression in triple negative breast cancer cell lines is associated with metastasis functions. Save
- IFN-γ IL-17A, or zonulin rapidly increase the permeability of the blood-brain and small intestinal epithelial barriers: Relevance for neuro-inflammatory diseases Save
- Nucleus accumbens-1/GADD45GIP1 axis mediates cisplatin resistance through cellular senescence in ovarian cancer Save
- CCNE1 amplification is associated with aggressive potential in endometrioid endometrial carcinomas Save
- Non-Hodgkin lymphoma of the female genital tract mimicking primary gynecological tumors: A single-center series of 3 cases Save
- Therapy-related myelodysplastic syndrome and acute myeloid leukemia following chemotherapy (paclitaxel and carboplatin) and radiation therapy in ovarian cancer: A case report Save