Ratnesh Tiwari

About

Medicinal chemist with over six years of research experience in small-molecule drug discovery, nucleic acid-targeted
therapeutics, and chemical biology. My research integrates synthetic organic chemistry, fluorescence spectroscopy,
and biophysical characterization to develop molecular probes and therapeutic agents for G-quadruplex DNA and
bacterial pathogens. I have authored ten peer-reviewed publications in leading international journals including Journal
of Physical Chemistry B, ACS Applied Bio Materials, Bioorganic Chemistry, and New Journal of Chemistry. I am
passionate about establishing an independent research program at the interface of medicinal chemistry, nucleic acid
chemistry, and translational drug discovery while contributing to undergraduate and postgraduate teaching.

Employment

Employment history is unavailable.

Education

• National Institute of Pharmaceutical Education and Research PhD
  2021 - Present
• National Institute of Pharmaceutical Education and Research M.S (Pharm)
  2019 - 2021
• Institute of Pharmacy Kanpur B. Pharm
  2015 - 2019

Projects & Funding

Projects & funding information is unavailable.

Publications (12)

• Designed NIR-I Emissive and Selective G-Quadruplex DNA Binder with Altered Organelle Specificity
  Biochemistry 2026 0 citations DOI: 10.1021/acs.biochem.6c00048
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• Hydroxy group modulated G-quadruplex binding, selectivity, and cellular uptake of styryl julolidine-benzothiazolium dyes
  Bioorganic Chemistry 2026 0 citations DOI: 10.1016/j.bioorg.2026.109798
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• Effect of dimerization on nucleic acid binding and sensing of a styryl-quinolinium molecular rotor: spectroscopic insights into aggregation
  New Journal of Chemistry 2026 0 citations DOI: 10.1039/d5nj04677g
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• Hyphenated mass spectroscopic detection of heavy metals in environmental and biological samples: A review
  Journal of Trace Elements and Minerals 2026 7 citations DOI: 10.1016/j.jtemin.2025.100273
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• A Highly Sensitive Benzimidazole-DNA-Based Biosensor for Intracellular Detection of Cu2+ Through a Ternary Complex Formation
  Chemistryselect 2025 3 citations DOI: 10.1002/slct.202502632
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• Fluorescence based metabisulfite sensing: New aspects of ion sensing by a styryl benzothiazolium dye and understanding nitrite interference
  Spectrochimica Acta Part A Molecular and Biomolecular Spectroscopy 2025 4 citations DOI: 10.1016/j.saa.2024.124821
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• Beyond telomeric G-quadruplexes: remarkable binding of PhenQE8 to promoter sequences
  New Journal of Chemistry 2024 1 citation DOI: 10.1039/d4nj02016b
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• Nile Blue: A Red-Emissive Fluorescent Dye That Displays Differential Self-Assembly and Binding to G-Quadruplexes
  The Journal of Physical Chemistry B 2023 10 citations DOI: 10.1021/acs.jpcb.3c05084
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• Parallel G-quadruplex recognition by neomycin
  Frontiers in Chemistry 2023 6 citations DOI: 10.3389/fchem.2023.1232514
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• Promoter G-Quadruplex Binding Styryl Benzothiazolium Derivative for Applications in Ligand Affinity Ranking and as Ethidium Bromide Substitute in Gel Staining
  ACS Applied Bio Materials 2023 11 citations DOI: 10.1021/acsabm.3c00060
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