MI

Madhumathi Irulappan

Christian Medical College & Hospital, Madurai Kamaraj University

ORCID iD 0000-0002-9856-604X
Follow

About

MADHUMATHI IRULAPPAN, Ph.D
Post-Doctoral Researcher, Department of Clinical Microbiology, Christian Medical College & Hospital, Vellore, Tamil Nadu, India.
Mobile: +91 9042479500, Email: [email protected]
linkedin.com/in/madhumathi-irulappan-b82001b6
https://twitter.com/IMMathii
Orcid ID: https://orcid.org/0000-0002-9856-604X

Research Experience:(Three year)
Post-Doctoral Researcher (August 2022 – Present) Christian Medical College, Vellore, TN
I work on the molecular genetics of antimicrobial resistance (AMR) in clinically significant bacterial pathogens under the mentorship of Prof. Balaji Veeraraghavan at the Department of Clinical Microbiology, Christian Medical College, Vellore. My research focuses on deciphering the genetic and evolutionary mechanisms underlying β-lactam and multidrug resistance, and exploring antibiotic-sparing interventions such as probiotics and bacteriophages for sustainable infection management

Education
Doctorate (Ph.D) in Molecular Biology (July– 2022)
Title: “Molecular Genetic Analyses of Drug Resistance in Escherichia coli: Genome-wide Sequence Analyses of a Potential Hygromycin B Resistant Mutant and their Implications.” at School of Biological Sciences, Madurai Kamaraj University, Madurai – 625021, India.

Research Publications (Accepted, awaiting online release):
Karthik Gunasekaran, Irulappan Madhumathi, Santhosh Raj, Greesma Grace Thomas, Venkatesh Narashiman, Vishnukumar Ramesh, Subbulakshmi Rajendran, Ramprakash Rayala, Ayyanraj Neeravi, Binesh Lal, Kamini Walia, Balaji Veeraraghavan Genetic Plasticity of Escherichia coli Causing Bloodstream Infections in India: A Focus on Phylogroups A to F IJMM (Accepted).

Fahad Khokhar, Xiaoliang Ba, Charlotte E Chong, P Malaka De Silva, Vignesh Shetty, Derek J Pickard, Claire Jenkins, Dhivya Murugan, Jobin Jacob John, Madhumathi Irulappan, Balaji Veeraraghavan, Agila Pragasam, Ankur Mutreja, Hilary MacQueen, Sushila Rigas, Mark A Holmes, Kate S Baker; A low resource requirement molecular diagnostic and surveillance tool for Shigella in the era of vaccination Nature Communications (Under review).

Irulappan Madhumathi, Vishnukumar Ramesh, Boomiga Rathakrishnan, Baby Abirami, Karthik Gunasekaran, T Sathish Kumar, Priyadharshini Jeyasankar, Gunachandru Raja, Karnan Selvam, Subbulakshmi Rajendran, Ayyanraj Neeravi, Ka mini Walia, Balaji Veeraraghavan; Safety and Efficacy Concerns in Indian Probiotics: Insights from Whole-Genome Sequencing and In vitro Assessment GUT Microbes_Reports (Under review).


Best Paper Awards: Nine Distinctions in National and International Conferences
• Research Fellowship: University Grants Commission, India (2015 - 2020): Secured the prestigious ‘Basic Scientific Research Fellowship’ for pursuing research in Molecular Genetic Analysis of Bacterial processes.
• Genetic evidence for the possible functional similarity between antibiotic Hygromycin and the Biological Toxin Doc in Escherichia coli and its Implications, International Conference on Bacterial Expressions, 12/01/15, Bangalore, Selected for special Oral Presentation
• Molecular Genetic Analysis of HygR Mutants of Escherichia coli Reveal a Possible Interlink Between Hygromycin Resistance and Programmed Cell Death in Bacteria, International Conference on Recent Trends in Biosciences, 04/07/16, Karaikudi, Best Oral Presentation Award
• Fosfomycin and aminoglycoside resistance co-carriage in carbapenem resistant E. coli and associated treatment complications, 12th Annual Research Day, 10/06/22, Vellore, First Prize in the poster presentation
• Molecular Genetic characterization of fosfomycin resistance mechanism and antibiotics combinations to combat AMR, MICROCON-2022, Bhubaneswar, Selected for Bacteriology Oral award
• The Pertussis Puzzle: Unraveling Resurgence and Vaccine Evolution for a Safer Future, MICROCON-2023, Lucknow, India; First Prize in Oral Presentation `
• Decoding Fosfomycin Resistance in E. coli and K. pneumoniae: Insights into Heterogeneous Mechanisms, Winter Symposium & South Zone MICROCON-2024, Vellore, Third Prize in Poster Presentation
• Inoculum Effect in Stenotrophomonas maltophilia: Implications for Antibiotic Efficacy and Treatment Strategies; CIDSCON-2025, NCPA, Mumbai, India; Third Prize in Poster Presentation
• Emergence of XDR Shigella In India: Clinical Correlates and Promising Oral Therapeutics; MICROCON-2025, New Delhi, India; Best Oral Presentation

Employment

  • Christian Medical College & Hospital Post-Doctoral fellow
    2022 - Present

Education

  • Madurai Kamaraj University PhD.,
  • Madurai Kamaraj University M.Sc., Genomics
    ? - 2011

Projects & Funding

Projects & funding information is unavailable.

Publications (13)