Reinner Omondi

About

I received my BSc (Hons) degree in Chemistry from Maseno University, Kenya and MSc degree in Bioinorganic Chemistry from the University of KwaZulu-Natal, South Africa. Currently I am working on a PhD degree under the supervision of Prof Stephen Ojwach and Prof Deogratius Jaganyi. My PhD research project involves the design and synthesis of palladium(II) complexes and investigation of their kinetics and mechanism of ligand substitution reactions, DNA/BSA protein interactions and cytotoxicity.

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Publications (11)

• Biomolecular interactions of 1,3-bis(2-arylimino)isoindolate-based palladium(II) complexes: Substitution kinetics, DNA/protein-binding, and molecular docking approaches
  Inorganica Chimica Acta 2023 DOI: 10.1016/j.ica.2023.121730
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• Quinolyl‐Based PGM Metallarectangles: Antiproliferative Activity, DNA and BSA Protein Interactions, and a Molecular Docking Perspective
  ChemBioChem 2023 DOI: 10.1002/cbic.202300271
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• Electronic and ring size effects of N-heterocyclic carbenes on the kinetics of ligand substitution reactions and DNA/protein interactions of their palladium(II) complexes
  BioMetals 2023 DOI: 10.1007/s10534-023-00507-8
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• Crystal Structures of Half-Sandwich Ru(II) Complexes, [(η6-pCymene)(3-chloro-6-(1H-pyrazol-1-yl)pyridazine)Ru(X)]BF4, (X = Cl, Br, I)
  2022
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• Chlorido-(η6-p-cymene)-(bis(pyrazol-1-yl)methane-κ2N,N′)Osmium(II) Tetrafluoroborate, C17H22BClF4N4Os
  Molbank 2022 DOI: 10.3390/M1429
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• Palladium(II) complexes of tridentate bis(benzazole) ligands: Structural, substitution kinetics, DNA interactions and cytotoxicity studies
  Reinner O. Omondi, Rajesh Bellam, Stephen Otieno Ojwach

  +2 more

  • Deogratius Jaganyi
  • Amos A. Fatokun
  Journal of Inorganic Biochemistry 2020 DOI: 10.1016/j.jinorgbio.2020.111156
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• Review of comparative studies of cytotoxic activities of Pt(II), Pd(II), Ru(II)/(III) and Au(III) complexes, their kinetics of ligand substitution reactions and DNA/BSA interactions
  Inorganica Chimica Acta 2020 DOI: 10.1016/j.ica.2020.119883
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• (Pyrazolyl)pyridine ruthenium(III) complexes: Synthesis, kinetics of substitution reactions with thiourea and biological studies
  Inorganic Chemistry Communications 2018 DOI: 10.1016/j.inoche.2018.06.006
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• (Pyridyl)benzoazole ruthenium(III) complexes: Kinetics of ligand substitution reaction and potential cytotoxic properties
  Inorganica Chimica Acta 2018 DOI: 10.1016/j.ica.2018.06.020
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• The effect of heteroatoms in the substitution reactions of (pyridyl)benzoazole ruthenium(III) complexes: A detailed kinetic and mechanistic study.
  The 9th International Conference of the Kenya Chemical Society 2017
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• Synthesis, substitution kinetics, DNA/BSA binding and cytotoxicity of tridentate N^E^N (E = NH, O, S) pyrazolyl palladium(II) complexes
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