Laura C. Murphy

Employment

• University of Edinburgh BioImage Analyst
  2017 - Present
• University of Cambridge Research Assistant
  2011 - 2012

Education

Education history is unavailable.

Projects & Funding

• Upgrade of Andor Dragonfly for Four Dimensional Cellular Medicine and Super-resolution microscopy Medical Research Council
  2022 - 2023

Publications (23)

• Polycomb Repressive Complexes 1 and 2 are recruited independently to pericentromeric heterochromatin in response to hypomethylation in mouse embryonic stem cells
  Silviya Dimova, Olga Stepanova, David Hay

  +7 more

  • Katherine E. Pickup
  • Philippe Emmanuel Gautier
  • Laura C. Murphy
  • Yatendra Kumar
  • Ian R. Adams
  • +2 more
  2025 DOI: 10.1101/2025.11.14.688451
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• Data analysis in imaging (DAIM) – A new RMS science section
  Journal of Microscopy 2024 DOI: 10.1111/jmi.13366
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• The crucial role of bioimage analysts in scientific research and publication
  Journal of Cell Science 2024 DOI: 10.1242/jcs.262322
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• ALDH1A3-acetaldehyde metabolism potentiates transcriptional heterogeneity in melanoma
  Cell Reports 2024 DOI: 10.1016/j.celrep.2024.114406
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• Ciliary tip actin dynamics regulate photoreceptor outer segment integrity
  Nature Communications 2024 DOI: 10.1038/s41467-024-48639-w
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• Ciliopathy patient variants reveal organelle-specific functions for TUBB4B in axonemal microtubules
  Daniel O Dodd, Sabrina Méchaussier, Patricia Levy Yeyati +80 more
  Science 2024 DOI: 10.1126/science.adf5489
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• DNMT3B PWWP mutations cause hypermethylation of heterochromatin
  EMBO Reports 2024 DOI: 10.1038/s44319-024-00061-5
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• Non‐fitting FLIM‐FRET facilitates analysis of protein interactions in live zebrafish embryos
  Journal of Microscopy 2023 DOI: 10.1111/jmi.13162
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• Signal-Retaining Autophagy Indicator as a Quantitative Imaging Method for ER-Phagy
  Cells 2023 DOI: 10.3390/cells12081134
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• Centriolar satellites expedite mother centriole remodeling to promote ciliogenesis
  eLife 2023 DOI: 10.7554/elife.79299
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• Ciliary tip actin dynamics regulate the cadence of photoreceptor disc formation
  2022 DOI: 10.1101/2022.11.10.516020
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• A WDR35-dependent coat protein complex transports ciliary membrane cargo vesicles to cilia.
  eLife 2021 DOI: 10.7554/elife.69786
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• Identification and functional modelling of plausibly causative cis-regulatory variants in a highly-selected cohort with X-linked intellectual disability
  PLOS ONE 2021 DOI: 10.1371/journal.pone.0256181
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• RAC1B modulates intestinal tumourigenesis via modulation of WNT and EGFR signalling pathways
  Nature Communications 2021 DOI: 10.1038/s41467-021-22531-3
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• A WDR35-dependent coatomer transports ciliary membrane proteins from the Golgi to the cilia
  2020 DOI: 10.1101/2020.12.22.423978
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• Fluorescent in vivo editing reporter (FIVER): A novel multispectral reporter of in vivo genome editing
  Peter A. Tennant, Robert G. Foster, Daniel O Dodd +12 more
  2020 DOI: 10.1101/2020.07.14.200170
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• Identification of a localized nonsense-mediated decay pathway at the endoplasmic reticulum.
  Genes & development 2020 DOI: 10.1101/gad.338061.120
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• DISC1 regulates N-methyl-D-aspartate receptor dynamics: abnormalities induced by a Disc1 mutation modelling a translocation linked to major mental illness.
  Translational psychiatry 2018 DOI: 10.1038/s41398-018-0228-1
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• Regulation of mitochondrial dynamics by DISC1, a putative risk factor for major mental illness.
  Schizophrenia research 2017 DOI: 10.1016/j.schres.2016.12.027
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• NDE1 and GSK3β Associate with TRAK1 and Regulate Axonal Mitochondrial Motility: Identification of Cyclic AMP as a Novel Modulator of Axonal Mitochondrial Trafficking.
  ACS chemical neuroscience 2016 DOI: 10.1021/acschemneuro.5b00255
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