TB
Thomas Benoist
Institut de Pharmacologie et de Biologie Structurale, University College London
Research areas: Biochemistry, Genetics and Molecular Biology · Molecular Biology · Mitochondrial Function and Pathology · Immune Response and Inflammation · Cellular Mechanics and Interactions
Employment
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Institut de Pharmacologie et de Biologie Structurale Postdoctoral Researcher2023 - Present
Education
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University College London PhD in Tissue Engineering and Regenerative Medicine2019 - 2023
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University College London Master of Pharmacy
Projects & Funding
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A lung, lymphoïd, liver on-a-chip system for modeling Tuberculosis vaccination response and infection. ANRS2026 - 2027
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Regeneration of the vascular network in whole organs for tissue engineering NIHR Great Ormond Street Hospital Biomedical Research Centre2019 - 2023
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Development of an organ-on-chip system for modeling tuberculosis and the testing of vaccine candidates Bill and Melinda Gates Foundation
Publications (7)
- Author Correction: Mitochondrial fission links ECM mechanotransduction to metabolic redox homeostasis and metastatic chemotherapy resistance Save
- Dual human lung models reveal compartment-specific activity of anti-tuberculosis drugs and host-directed therapies Save
- Portimine A toxin causes skin inflammation through ZAKα-dependent NLRP1 inflammasome activation Save
- Lung viral infection modelling in a bioengineered whole-organ Save
- Mitochondrial fission links ECM mechanotransduction to metabolic redox homeostasis and metastatic chemotherapy resistance Save
- A TAK1-Driven NLRP1 Inflammasome Pathway Revealed by Phosphatase-Targeting Environmental Toxins Save
- Neutrophil myeloperoxidase as a functional biomarker for RSV severity: implications for in vitro therapeutic screening Save