Dr. Jonathan Mandolo
Research areas: Medicine · Infectious Diseases · Viral gastroenteritis research and epidemiology · SARS-CoV-2 and COVID-19 Research · COVID-19 Clinical Research Studies
0000-0003-0143-7469
About
Jonathan Mandolo is a clinical scientist with expertise in serology, epidemiology, molecular biology, Bioinformatics, and vaccine evaluation. Skilled in developing and validating multiplex serological assays to assess pathogen transmission dynamics, vaccine coverage, and effectiveness for key vaccine-preventable diseases, including Typhoidal Salmonella, Cholera, Rotavirus, SARS-CoV-2, Diphtheria, Tetanus, Measles, Rubella, and Pertussis. Experienced in immunoassay development, advanced data analysis using R statistical software, and leading multi-site research projects. Author of 21 peer-reviewed publications, including four as first author, published in high-impact journals. Delivered numerous oral and poster presentations at national and international scientific conferences and recognised through several international travel grants for contributions to global health research.
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Education
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Publications (25)
- Using serosurveillance to estimate transmission, population immunity, and vaccine coverage for key enteric pathogens in Malawi. Save
- Distribution of Rotavirus alphagastroenteritidis Strains in Blantyre, Malawi, During and After the COVID-19 Pandemic Save
- Maternal-infant rotavirus-specific antibody kinetics to inform timing of vaccine boosting in Malawi: An observational study Save
- Early-life gut microbiome associates with positive vaccine take and shedding in neonatal schedule of the human neonatal rotavirus vaccine RV3-BB Save
- Kinetics of rotavirus-specific IgA and IgG at an individual and population level in Malawi [version 1] Save
- Age-specific immunity to rotavirus infection and the risk of disease before and after rotavirus vaccine introduction in the United Kingdom: an observational, seroepidemiological study Save
- Rotavirus-Specific Maternal Serum Antibodies and Vaccine Responses to RV3-BB Rotavirus Vaccine Administered in a Neonatal or Infant Schedule in Malawi Save
- Longevity of hybrid immunity against SARS-CoV-2 in adults vaccinated with an adenovirus-based COVID-19 vaccine Save
- Association Between Maternal Breastmilk Microbiota Composition and Rotavirus Vaccine Response in African, Asian, and European Infants: A Prospective Cohort Study Save
- Comparative whole genome analysis reveals re-emergence of human Wa-like and DS-1-like G3 rotaviruses after Rotarix vaccine introduction in Malawi Save
- Acute rotavirus infection is associated with the induction of circulating memory CD4+ T cell subsets Save
- Omicron B.1.1.529 variant infections associated with severe disease are uncommon in a COVID-19 under-vaccinated, high SARS-CoV-2 seroprevalence population in Malawi Save
- AstraZeneca COVID-19 vaccine induces robust broadly cross-reactive antibody responses in Malawian adults previously infected with SARS-CoV-2 Save
- Association between maternal breastmilk microbiota composition and rotavirus vaccine response in African, Asian, and European infants: a prospective cohort study Save
- Plasma Rotavirus-specific IgA and Risk of Rotavirus Vaccine Failure in Infants in Malawi Save
- Rotavirus Genotypes in Hospitalized Children With Acute Gastroenteritis Before and After Rotavirus Vaccine Introduction in Blantyre, Malawi, 1997–2019 Save
- Neonatal rotavirus vaccine (RV3-BB) immunogenicity and safety in a neonatal and infant administration schedule in Malawi: a randomised, double-blind, four-arm parallel group dose-ranging study Save
- Impact of maternal antibodies and microbiota development on the immunogenicity of oral rotavirus vaccine in African, Indian, and European infants Save
- Reduction in Severity of All-Cause Gastroenteritis Requiring Hospitalisation in Children Vaccinated against Rotavirus in Malawi Save
- SARS-CoV-2 exposure in Malawian blood donors: an analysis of seroprevalence and variant dynamics between January 2020 and July 2021 Save