Varsha Dilip Shiragannavar

About

As a passionate researcher, I have investigated how bioactive compounds modulate key molecular pathways involved in MASLD and HCC. My work has focused on deciphering the interplay between metabolism, inflammation, and cancer progression using advanced cellular and animal models. Through this research, I have developed strong expertise in molecular pathway analysis and experimental disease modeling to identify innovative therapeutic strategies for metabolic and liver diseases.

Employment

• JSS Medical College Research Project Assistant
  2020 - 2023

Education

• Yuvaraja College University of Mysore Bachelor's student
  2014 - 2017

Projects & Funding

Projects & funding information is unavailable.

Publications (17)

• In-depth analysis of self-assembly processes in in vitro spheroidal and organoid systems mechanisms and drug development
  Preclinical Cancer Models for Translational Research and Drug Development 2025 DOI: 10.1007/978-981-97-5742-8_4
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• Phytochemicals to Target Sorafenib Resistance Pathways in Liver Cancer
  Liver Cancer and Phytomedicine Chemoprevention Chemo Sensitization and Chemotherapy Strategies 2025 DOI: 10.1142/9789811293320_0005
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• In-Depth Analysis of Self-Assembly Processes in In Vitro Spheroidal and Organoid Systems Mechanisms and Drug Development
  2025 DOI: 10.1007/978-981-97-5742-8_4
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• Dissecting microRNA-regulated networks in hepatocellular carcinoma cell subtypes with different mutational profiles: Evidence from in vitro and in silico studies
  Research Square 2024 DOI: 10.21203/rs.3.rs-4347735/v1
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• Novel role of Quercetin in ameliorating metabolic syndrome via VDR mediated activation of adiponectin/AdipoR2 signaling
  Biochemistry and Biophysics Reports 2024 DOI: 10.1016/j.bbrep.2024.101754
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• Unraveling Key Signaling Pathways Altered in Hepatocellular Carcinoma
  Gene Expression the Journal of Liver Research 2023 DOI: 10.14218/GE.2022.00009S
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• The ameliorating effect of withaferin A on high-fat diet-induced non-alcoholic fatty liver disease by acting as an LXR/FXR dual receptor activator
  Frontiers in Pharmacology 2023 DOI: 10.3389/fphar.2023.1135952
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• Telomerase, an Accomplice of RNA-induced Silencing Complex in Hepatocellular Carcinoma
  Gene Expression the Journal of Liver Research 2023 DOI: 10.14218/GE.2022.00010
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• Quercetin activates vitamin D receptor and ameliorates breast cancer induced hepatic inflammation and fibrosis
  Frontiers in Nutrition 2023 DOI: 10.3389/fnut.2023.1158633
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• Discovery of eukaryotic cellular receptor for Withaferin A, a multifaceted drug from Withania somnifera plant
  Medicine in Drug Discovery 2022 DOI: 10.1016/j.medidd.2022.100127
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